Chlorine in PDB 6iz1: Crystal Structure Analysis of A Eukaryotic Membrane Protein

The structure of Crystal Structure Analysis of A Eukaryotic Membrane Protein, PDB code: 6iz1 was solved by X.H.Wang, Y.Zeng, F.Gao, M.Su, Y.H.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.49 / 2.40
Space group	P 63 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.348, 127.348, 101.801, 90.00, 90.00, 120.00
R / Rfree (%)	21.7 / 25.7

The structure of Crystal Structure Analysis of A Eukaryotic Membrane Protein also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Crystal Structure Analysis of A Eukaryotic Membrane Protein (pdb code 6iz1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure Analysis of A Eukaryotic Membrane Protein, PDB code: 6iz1:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:52.8 occ:0.90 O A:HOH553 2.9 59.1 0.5 O A:HOH545 3.0 53.3 1.0 CD2 A:HIS142 4.3 55.6 1.0 CB A:HIS142 4.3 56.8 1.0 CG A:HIS142 4.4 56.6 1.0 O A:HOH516 4.7 50.3 0.5 ND1 A:HIS143 4.8 67.2 1.0

Chlorine binding site 2 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:65.4 occ:0.70 O A:HOH558 3.0 70.8 1.0 NZ A:LYS155 3.2 58.8 1.0 O A:HOH554 3.3 84.7 1.0 ND1 A:HIS136 3.6 73.8 1.0 CA A:GLY133 3.7 53.7 1.0 CD A:LYS155 3.9 55.3 1.0 O A:ALA132 3.9 59.2 1.0 CB A:HIS136 3.9 58.9 1.0 N A:GLY133 3.9 56.7 1.0 CE A:LYS155 4.0 58.4 1.0 C A:ALA132 4.1 58.0 1.0 CG A:HIS136 4.1 70.9 1.0 CG A:LYS155 4.2 54.6 1.0 CB A:ALA69 4.6 46.0 1.0 CE1 A:HIS136 4.6 73.2 1.0 CG2 A:THR151 4.8 46.6 1.0 C A:GLY133 4.8 59.3 1.0 CB A:ALA132 4.8 47.9 1.0 O A:GLY133 4.9 60.1 1.0

Chlorine binding site 3 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:68.3 occ:0.50 NH2 A:ARG174 3.0 0.8 1.0 NH1 A:ARG170 3.2 73.8 1.0 NH1 A:ARG174 3.4 0.9 1.0 NE2 A:GLN167 3.4 83.9 1.0 NH2 A:ARG170 3.4 72.2 1.0 CZ A:ARG174 3.6 0.9 1.0 CZ A:ARG170 3.8 71.8 1.0 CD A:PRO41 3.9 72.8 1.0 CG A:PRO41 4.2 72.5 1.0 CD A:GLN167 4.3 77.3 1.0 CG A:GLN167 4.3 72.0 1.0 CG1 A:VAL172 4.3 77.0 1.0 NE A:ARG174 4.8 0.0 1.0 CG2 A:VAL172 4.9 73.8 1.0 CB A:VAL172 5.0 76.3 1.0

Chlorine binding site 4 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:65.8 occ:0.50 N A:PHE52 3.4 69.4 1.0 CB A:PHE52 3.5 65.8 1.0 CD A:PRO51 3.5 71.7 1.0 CG A:PRO51 3.8 67.0 1.0 N A:PRO51 3.9 74.7 1.0 CA A:PHE52 4.0 68.5 1.0 C A:SER50 4.2 76.9 1.0 CA A:SER50 4.3 76.8 1.0 C A:PRO51 4.4 69.9 1.0 CA A:PRO51 4.6 69.8 1.0 CB A:PRO51 4.8 65.4 1.0 CG A:PHE52 4.8 67.6 1.0 O A:SER50 4.9 74.3 1.0 N A:ALA53 4.9 65.1 1.0 O A:LYS49 5.0 84.2 1.0

Chlorine binding site 5 out of 5 in the Crystal Structure Analysis of A Eukaryotic Membrane Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure Analysis of A Eukaryotic Membrane Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:57.2 occ:0.60 NZ A:LYS155 3.1 58.8 1.0 OH A:TYR66 3.3 79.1 1.0 CE1 A:TYR66 3.4 64.0 1.0 O A:HOH561 3.6 95.7 1.0 CB A:ALA132 3.7 47.9 1.0 CE A:LYS155 3.8 58.4 1.0 CG A:GLN129 3.8 50.0 1.0 CZ A:TYR66 3.8 70.4 1.0 CA A:GLN129 4.0 62.8 1.0 O A:HOH550 4.0 89.7 1.0 CB A:GLN129 4.4 50.0 1.0 O A:HOH523 4.5 98.1 1.0 CD1 A:TYR66 4.6 61.7 1.0 O A:GLN129 4.6 60.3 1.0 O A:ARG128 4.6 59.0 1.0 N A:GLN129 4.7 61.5 1.0 C A:GLN129 4.8 61.4 1.0 C A:ARG128 5.0 63.2 1.0

X.H.Wang, M.Su, F.Gao, W.Xie, Y.Zeng, D.L.Li, X.L.Liu, H.Zhao, L.Qin, F.Li, Q.Liu, O.B.Clarke, S.M.Lam, G.H.Shui, W.A.Hendrickson, Y.H.Chen. Structural Basis For Activity of Tric Counter-Ion Channels in Calcium Release. Proc.Natl.Acad.Sci.Usa V. 116 4238 2019.
ISSN: ESSN 1091-6490
PubMed: 30770441
DOI: 10.1073/PNAS.1817271116