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Chlorine in PDB 6jxt: Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization
Enzymatic activity of Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization
All present enzymatic activity of Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization:
2.7.10.1;
2.7.10.1;
Protein crystallography data
The structure of Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization, PDB code: 6jxt
was solved by
C.H.Yun,
S.J.Zhu,
X.E.Yan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 43.38 / 2.31 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 86.749, 86.749, 103.939, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 21.7 / 23.9 |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization
(pdb code 6jxt). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization, PDB code: 6jxt:
In total only one binding site of Chlorine was determined in the Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization, PDB code: 6jxt:
Chlorine binding site 1 out of 1 in 6jxt
Go back to
Chlorine Binding Sites List in 6jxt
Chlorine binding site 1 out
of 1 in the Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Egfr 696-1022 Wt in Complex with AZD9291 Prepared By Cocrystallization within 5.0Å range:
|
Reference:
C.H.Yun,
S.J.Zhu,
X.E.Yan.
Structural Basis of the Selectivity of the Drug Molecule AZD9291 For the T790M Cancer Mutant of Egfr To Be Published.
Page generated: Sun Jul 28 02:21:15 2024
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