Chlorine in PDB 6ke4: Abloop Reengineered Ferritin Nanocage

All present enzymatic activity of Abloop Reengineered Ferritin Nanocage:
1.16.3.1;

The structure of Abloop Reengineered Ferritin Nanocage, PDB code: 6ke4 was solved by W.M.Wang, H.F.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.44 / 2.30
Space group	F 4 3 2
Cell size a, b, c (Å), α, β, γ (°)	182.642, 182.642, 182.642, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 23.6

The structure of Abloop Reengineered Ferritin Nanocage also contains other interesting chemical elements:

Magnesium	(Mg)	3 atoms
Iron	(Fe)	2 atoms
Calcium	(Ca)	1 atom

The binding sites of Chlorine atom in the Abloop Reengineered Ferritin Nanocage (pdb code 6ke4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Abloop Reengineered Ferritin Nanocage, PDB code: 6ke4:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Abloop Reengineered Ferritin Nanocage


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Abloop Reengineered Ferritin Nanocage within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl206 b:48.2 occ:1.00 OG A:SER32 3.8 27.9 1.0 CB A:SER32 4.4 16.6 1.0 N A:TYR33 4.7 13.2 1.0 C A:SER32 4.8 15.3 1.0 CA A:TYR33 4.9 12.0 1.0 O A:LEU29 4.9 11.7 1.0 CD2 A:LEU36 5.0 8.9 1.0 O A:SER32 5.0 13.5 1.0

Chlorine binding site 2 out of 2 in the Abloop Reengineered Ferritin Nanocage


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Abloop Reengineered Ferritin Nanocage within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl207 b:38.6 occ:1.00 ND2 A:ASN22 3.1 10.6 1.0 CA A:ALA19 3.6 13.5 1.0 CB A:ASN22 3.8 14.8 1.0 CD2 A:PHE79 3.8 39.1 1.0 CB A:ALA19 3.9 14.0 1.0 CG A:ASN22 3.9 16.4 1.0 CB A:PHE79 4.2 19.1 1.0 O A:ALA19 4.2 17.1 1.0 O A:HOH318 4.3 24.6 1.0 C A:ALA19 4.4 14.9 1.0 CG A:PHE79 4.5 56.5 1.0 N A:ALA19 4.6 11.9 1.0 O A:GLU18 4.8 13.2 1.0 CE2 A:PHE79 4.8 32.5 1.0 O A:HOH327 4.8 21.4 1.0

W.Wang, L.Wang, G.Li, G.Zhao, X.Zhao, H.Wang. Ab Loop Engineered Ferritin Nanocages For Drug Loading Under Benign Experimental Conditions. Chem.Commun.(Camb.) V. 55 12344 2019.
ISSN: ESSN 1364-548X
PubMed: 31556881
DOI: 10.1039/C9CC05247J