Chlorine in PDB 6kkr: Human KCC1 Structure Determined in Kcl and Detergent Gdn

The structure of Human KCC1 Structure Determined in Kcl and Detergent Gdn also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Chlorine atom in the Human KCC1 Structure Determined in Kcl and Detergent Gdn (pdb code 6kkr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Human KCC1 Structure Determined in Kcl and Detergent Gdn, PDB code: 6kkr:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Human KCC1 Structure Determined in Kcl and Detergent Gdn


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human KCC1 Structure Determined in Kcl and Detergent Gdn within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1105 b:56.0 occ:1.00 OH A:TYR589 2.5 46.3 1.0 N A:GLY433 3.2 52.2 1.0 CE1 A:PHE205 3.5 47.3 1.0 CZ A:TYR589 3.5 46.3 1.0 N A:ILE434 3.5 56.1 1.0 CG A:MET435 3.6 60.1 1.0 N A:MET435 3.6 60.1 1.0 CA A:GLY433 3.7 52.2 1.0 CE1 A:TYR589 3.8 46.3 1.0 CB A:MET435 3.8 60.1 1.0 CE1 A:PHE585 3.8 41.9 1.0 C A:GLY433 3.9 52.2 1.0 CD1 A:PHE585 4.0 41.9 1.0 CD1 A:PHE205 4.1 47.3 1.0 C A:THR432 4.3 46.2 1.0 CA A:MET435 4.3 60.1 1.0 CB A:THR432 4.4 46.2 1.0 CA A:ILE434 4.4 56.1 1.0 CZ A:PHE205 4.5 47.3 1.0 C A:ILE434 4.5 56.1 1.0 CA A:THR432 4.5 46.2 1.0 CB A:ILE434 4.7 56.1 1.0 CE2 A:TYR589 4.7 46.3 1.0 CZ A:PHE585 4.8 41.9 1.0 O A:GLY433 5.0 52.2 1.0

Chlorine binding site 2 out of 4 in the Human KCC1 Structure Determined in Kcl and Detergent Gdn


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human KCC1 Structure Determined in Kcl and Detergent Gdn within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1107 b:52.1 occ:1.00 N A:VAL135 3.1 46.6 1.0 CA A:GLY134 3.4 47.7 1.0 N A:ILE136 3.5 45.3 1.0 C A:GLY134 3.5 47.7 1.0 O A:PRO429 3.6 41.0 1.0 CA A:SER430 3.8 43.9 1.0 K A:K1106 3.9 48.2 1.0 N A:GLY134 3.9 47.7 1.0 CG1 A:VAL135 3.9 46.6 1.0 CB A:ILE136 4.1 45.3 1.0 CG1 A:ILE136 4.1 45.3 1.0 CA A:VAL135 4.1 46.6 1.0 OG A:SER430 4.1 43.9 1.0 OH A:TYR216 4.3 42.9 1.0 C A:PRO429 4.3 41.0 1.0 CD1 A:ILE136 4.3 45.3 1.0 C A:VAL135 4.3 46.6 1.0 CE1 A:TYR216 4.3 42.9 1.0 O A:ILE132 4.4 47.0 1.0 N A:SER430 4.4 43.9 1.0 CA A:ILE136 4.4 45.3 1.0 CB A:SER430 4.4 43.9 1.0 O A:GLY134 4.5 47.7 1.0 CB A:VAL135 4.6 46.6 1.0 C A:PHE133 4.6 47.2 1.0 CE A:MET215 4.8 39.7 1.0 CZ A:TYR216 4.8 42.9 1.0 C A:SER430 4.8 43.9 1.0 O A:SER430 4.9 43.9 1.0 N A:LEU137 4.9 45.4 1.0

Chlorine binding site 3 out of 4 in the Human KCC1 Structure Determined in Kcl and Detergent Gdn


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Human KCC1 Structure Determined in Kcl and Detergent Gdn within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1105 b:55.7 occ:1.00 OH B:TYR589 2.5 46.3 1.0 N B:GLY433 3.2 52.2 1.0 CE1 B:PHE205 3.5 47.4 1.0 CZ B:TYR589 3.5 46.3 1.0 N B:ILE434 3.5 56.2 1.0 CG B:MET435 3.6 60.3 1.0 N B:MET435 3.6 60.3 1.0 CA B:GLY433 3.7 52.2 1.0 CE1 B:TYR589 3.8 46.3 1.0 CB B:MET435 3.8 60.3 1.0 CE1 B:PHE585 3.8 42.2 1.0 C B:GLY433 3.9 52.2 1.0 CD1 B:PHE585 4.0 42.2 1.0 CD1 B:PHE205 4.1 47.4 1.0 C B:THR432 4.3 46.4 1.0 CA B:MET435 4.3 60.3 1.0 CB B:THR432 4.4 46.4 1.0 CA B:ILE434 4.4 56.2 1.0 CZ B:PHE205 4.5 47.4 1.0 C B:ILE434 4.5 56.2 1.0 CA B:THR432 4.5 46.4 1.0 CB B:ILE434 4.7 56.2 1.0 CE2 B:TYR589 4.7 46.3 1.0 CZ B:PHE585 4.8 42.2 1.0 O B:GLY433 5.0 52.2 1.0

Chlorine binding site 4 out of 4 in the Human KCC1 Structure Determined in Kcl and Detergent Gdn


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Human KCC1 Structure Determined in Kcl and Detergent Gdn within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1107 b:52.9 occ:1.00 N B:VAL135 3.1 47.1 1.0 CA B:GLY134 3.4 48.2 1.0 N B:ILE136 3.5 45.8 1.0 C B:GLY134 3.5 48.2 1.0 O B:PRO429 3.6 41.5 1.0 CA B:SER430 3.8 44.3 1.0 K B:K1106 3.9 48.6 1.0 N B:GLY134 3.9 48.2 1.0 CG1 B:VAL135 3.9 47.1 1.0 CB B:ILE136 4.1 45.8 1.0 CG1 B:ILE136 4.1 45.8 1.0 CA B:VAL135 4.1 47.1 1.0 OG B:SER430 4.1 44.3 1.0 OH B:TYR216 4.3 43.3 1.0 C B:PRO429 4.3 41.5 1.0 CD1 B:ILE136 4.3 45.8 1.0 C B:VAL135 4.3 47.1 1.0 CE1 B:TYR216 4.3 43.3 1.0 O B:ILE132 4.3 47.3 1.0 N B:SER430 4.4 44.3 1.0 CA B:ILE136 4.4 45.8 1.0 CB B:SER430 4.4 44.3 1.0 O B:GLY134 4.5 48.2 1.0 C B:PHE133 4.6 47.6 1.0 CB B:VAL135 4.6 47.1 1.0 CE B:MET215 4.8 40.2 1.0 CZ B:TYR216 4.8 43.3 1.0 C B:SER430 4.8 44.3 1.0 O B:SER430 4.9 44.3 1.0 N B:LEU137 4.9 46.0 1.0

S.Liu, S.Chang, B.Han, L.Xu, M.Zhang, C.Zhao, W.Yang, F.Wang, J.Li, E.Delpire, S.Ye, X.C.Bai, J.Guo. Cryo-Em Structures of the Human Cation-Chloride Cotransporter KCC1. Science V. 366 505 2019.
ISSN: ESSN 1095-9203
PubMed: 31649201
DOI: 10.1126/SCIENCE.AAY3129