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Chlorine in PDB 6ko1: The Crystal Structue of PDE10A Complexed with 2DEnzymatic activity of The Crystal Structue of PDE10A Complexed with 2D
All present enzymatic activity of The Crystal Structue of PDE10A Complexed with 2D:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of The Crystal Structue of PDE10A Complexed with 2D, PDB code: 6ko1
was solved by
Y.-Y.Huang,
Y.F.Yu,
C.Zhang,
L.Guo,
D.Wu,
H.-B.Luo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ko1:
The structure of The Crystal Structue of PDE10A Complexed with 2D also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the The Crystal Structue of PDE10A Complexed with 2D
(pdb code 6ko1). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Crystal Structue of PDE10A Complexed with 2D, PDB code: 6ko1: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6ko1Go back to Chlorine Binding Sites List in 6ko1
Chlorine binding site 1 out
of 2 in the The Crystal Structue of PDE10A Complexed with 2D
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6ko1Go back to Chlorine Binding Sites List in 6ko1
Chlorine binding site 2 out
of 2 in the The Crystal Structue of PDE10A Complexed with 2D
Mono view Stereo pair view
Reference:
Y.F.Yu,
C.Zhang,
Y.Y.Huang,
S.Zhang,
Q.Zhou,
X.Li,
Z.Lai,
Z.Li,
Y.Gao,
Y.Wu,
L.Guo,
D.Wu,
H.B.Luo.
Discovery and Optimization of Chromone Derivatives As Novel Selective Phosphodiesterase 10 Inhibitors. Acs Chem Neurosci 2020.
Page generated: Sat Dec 12 13:13:44 2020
ISSN: ESSN 1948-7193 PubMed: 32105440 DOI: 10.1021/ACSCHEMNEURO.0C00024 |
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