Chlorine in PDB 6ksf: Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge

The structure of Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge, PDB code: 6ksf was solved by H.Li, M.Zhang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.89 / 2.40
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	67.482, 67.482, 263.641, 90.00, 90.00, 90.00
R / Rfree (%)	22.8 / 27.2

The binding sites of Chlorine atom in the Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge (pdb code 6ksf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge, PDB code: 6ksf:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:42.2 occ:1.00 NE A:ARG283 3.1 42.9 1.0 NH2 A:ARG283 3.2 38.2 1.0 NE A:ARG344 3.3 37.3 1.0 NH1 A:ARG344 3.4 41.2 1.0 CZ A:ARG283 3.5 39.6 1.0 CB A:ASP233 3.6 46.0 1.0 CZ A:ARG344 3.8 45.1 1.0 OD2 A:ASP233 3.9 52.9 1.0 CG A:ASP233 4.0 50.2 1.0 SG A:CYS235 4.1 61.1 1.0 CD1 A:LEU243 4.2 34.6 1.0 CD A:ARG283 4.2 35.8 1.0 CD1 A:LEU237 4.2 52.1 1.0 SG B:XL3101 4.3 60.7 1.0 CD A:ARG344 4.4 36.8 1.0 NH1 A:ARG283 4.8 45.9 1.0 OD1 A:ASP233 5.0 48.9 1.0 O A:ARG283 5.0 31.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of ALKBH1 Bound to 21-Mer Dna Bulge within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:36.7 occ:0.50 N A:PHE281 3.2 29.3 1.0 CB A:PHE281 3.7 29.6 1.0 CA A:GLY280 3.9 29.7 1.0 C A:GLY280 4.1 31.4 1.0 CA A:PHE281 4.1 31.6 1.0 O A:PRO97 4.3 31.4 1.0 CB A:PRO97 4.3 28.0 1.0 C A:PRO97 4.4 33.5 1.0 N A:GLY98 4.6 30.1 1.0 O A:SER279 4.6 32.6 1.0 CG A:PRO97 4.7 30.3 1.0 CA A:GLY98 4.8 33.9 1.0 N A:GLY280 4.8 30.8 1.0

M.Zhang, S.Yang, R.Nelakanti, W.Zhao, G.Liu, Z.Li, X.Liu, T.Wu, A.Xiao, H.Li. Mammalian ALKBH1 Serves As An N6-Ma Demethylase of Unpairing Dna. Cell Res. V. 30 197 2020.
ISSN: ISSN 1001-0602
PubMed: 32051560
DOI: 10.1038/S41422-019-0237-5