Chlorine in PDB 6lsc: Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model

The structure of Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model, PDB code: 6lsc was solved by H.H.Lim, T.Shane, C.Miller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.43 / 3.21
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	90.702, 85.166, 100.092, 90.00, 102.61, 90.00
R / Rfree (%)	21 / 26.3

The binding sites of Chlorine atom in the Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model (pdb code 6lsc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model, PDB code: 6lsc:

Chlorine binding site 1 out of 1 in the Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the E202Y Mutant of the Cl-/H+ Antiporter Clc-EC1 From E.Coli: A Re-Refined Model of the 4FTP Model within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:0.4 occ:1.00 OH A:TYR445 2.5 0.2 1.0 OG A:SER107 2.8 98.4 1.0 N A:ILE356 3.1 85.2 1.0 CA A:GLY355 3.3 90.1 1.0 CZ A:TYR445 3.6 98.3 1.0 CB A:SER107 3.7 98.8 1.0 C A:GLY355 3.7 86.0 1.0 CB A:PHE357 3.7 91.0 1.0 N A:PHE357 3.7 91.9 1.0 OE2 A:GLU148 3.9 95.4 1.0 CE1 A:TYR445 4.0 91.9 1.0 C A:ILE356 4.1 91.3 1.0 CA A:ILE356 4.1 89.3 1.0 CG A:GLU148 4.2 0.5 1.0 CA A:GLY149 4.2 93.2 1.0 CG2 A:ILE356 4.3 91.7 1.0 CA A:PHE357 4.3 89.9 1.0 N A:GLY149 4.3 96.0 1.0 CD2 A:PHE357 4.3 0.4 1.0 CA A:SER107 4.3 0.7 1.0 CG A:PHE357 4.5 95.8 1.0 CD1 A:ILE109 4.5 0.5 1.0 CD A:GLU148 4.5 0.1 1.0 CB A:ILE356 4.7 97.4 1.0 N A:GLY355 4.7 88.5 1.0 CE2 A:TYR445 4.8 92.4 1.0 O A:ILE356 4.9 0.9 1.0 O A:GLY355 4.9 93.3 1.0 C A:GLU148 4.9 93.8 1.0 CG1 A:ILE109 5.0 0.9 1.0

H.H.Lim, T.Shane, C.Miller. Intracellular Proton Access in A Cl(-)/H(+) Antiporter. Plos Biol. V. 10 01441 2012.
ISSN: ESSN 1545-7885
DOI: 10.1371/JOURNAL.PBIO.1001441