Chlorine in PDB 6m38: X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form

The structure of X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form, PDB code: 6m38 was solved by P.Shabareesh, A.K.Mallela, D.Joseph, A.Penmatsa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.64 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	97.288, 140.641, 167.818, 90, 90, 90
R / Rfree (%)	21.5 / 24.4

The structure of X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form (pdb code 6m38). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form, PDB code: 6m38:

Chlorine binding site 1 out of 1 in the X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of A Drosophila Dopamine Transporter with Subsiteb Mutations (D121G/S426M) in S-Duloxetine Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl604 b:74.2 occ:1.00 OG A:SER320 3.1 72.4 1.0 OH A:TYR69 3.1 75.8 1.0 OG A:SER356 3.1 65.7 1.0 CB A:SER320 3.4 69.4 1.0 NE2 A:GLN316 3.7 72.3 1.0 CB A:SER356 3.8 65.3 1.0 CD1 A:PHE53 3.9 63.1 1.0 CZ A:TYR69 4.0 76.5 1.0 CE1 A:TYR69 4.0 70.9 1.0 CG A:GLN316 4.0 66.6 1.0 CB A:PHE53 4.1 61.4 1.0 CG A:PHE53 4.3 65.7 1.0 CD A:GLN316 4.3 71.0 1.0 ND2 A:ASN352 4.4 68.8 1.0 CE1 A:PHE53 4.7 64.7 1.0 ND2 A:ASN49 4.8 61.8 1.0 CG A:ASN49 4.8 63.8 1.0 O A:GLN316 4.9 65.0 1.0 CA A:SER320 4.9 74.6 1.0 CA A:ASN49 4.9 65.7 1.0

P.Shabareesh, A.K.Mallela, D.Joseph. Structural Basis of Norepinephrine Recognition and Transport Inhibition in Neurotransmitter Transporters To Be Published.