Chlorine in PDB 6m3z: X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form

The structure of X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form, PDB code: 6m3z was solved by P.Shabareesh, A.K.Mallela, D.Joseph, A.Penmatsa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.55 / 3.11
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	96.997, 141.599, 168.249, 90, 90, 90
R / Rfree (%)	22.2 / 26.4

The structure of X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form (pdb code 6m3z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form, PDB code: 6m3z:

Chlorine binding site 1 out of 1 in the X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of A Drosophila Dopamine Transporter with Net-Like Mutations (D121G/S426M/F471L) in Milnacipran Bound Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl704 b:78.9 occ:1.00 OG A:SER320 3.0 75.5 1.0 OG A:SER356 3.2 80.2 1.0 OH A:TYR69 3.4 71.3 1.0 NE2 A:GLN316 3.5 75.2 1.0 CB A:SER320 3.5 73.9 1.0 CG A:GLN316 3.8 74.1 1.0 CB A:SER356 4.0 74.2 1.0 CD A:GLN316 4.1 75.1 1.0 CB A:PHE53 4.2 71.2 1.0 CZ A:TYR69 4.2 77.7 1.0 CE1 A:TYR69 4.3 78.1 1.0 CD1 A:PHE53 4.4 78.0 1.0 CG A:PHE53 4.5 72.1 1.0 CG A:ASN49 4.8 74.4 1.0 O A:GLN316 4.8 77.9 1.0 CA A:ASN49 4.8 76.2 1.0 ND2 A:ASN352 4.9 81.0 1.0 OD1 A:ASN49 4.9 74.9 1.0 ND2 A:ASN49 4.9 74.9 1.0 OD1 A:ASN352 5.0 87.8 1.0

P.Shabareesh, A.K.Mallela, D.Joseph. Structural Basis of Norepinephrine Recognition and Transport Inhibition in Neurotransmitter Transporters To Be Published.