Chlorine in PDB 6mfp: Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1

The structure of Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1, PDB code: 6mfp was solved by W.D.Tolbert, B.Young, M.Pazgier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.60 / 3.00
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	63.487, 80.093, 88.688, 84.82, 82.33, 82.24
R / Rfree (%)	21.4 / 27.4

The binding sites of Chlorine atom in the Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1 (pdb code 6mfp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1, PDB code: 6mfp:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl512 b:89.7 occ:1.00 OD2 A:ASP107 3.3 94.2 1.0 OD1 A:ASP107 3.6 97.3 1.0 O A:LEU52 3.9 73.7 1.0 CG A:ASP107 3.9 91.0 1.0 CA A:PHE53 4.9 67.5 1.0 C A:LEU52 5.0 68.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the RV305 C1-C2 Specific Adcc Potent Antibody DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl301 b:97.3 occ:1.00 OE1 D:GLN37 3.5 58.8 1.0 OE2 D:GLU45 3.5 0.2 1.0 CD D:PRO59 4.5 87.6 1.0 CD D:GLN37 4.6 59.7 1.0 CD2 D:LEU47 4.7 64.9 1.0 CD D:GLU45 4.8 0.9 1.0

W.D.Tolbert, B.Young, M.Pazgier. Crystal Structure of Adcc Potent DH677.3 Fab in Complex with Hiv-1 Clade A/E GP120 and M48U1 To Be Published.