Chlorine in PDB 6mjh: The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States

The structure of The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States, PDB code: 6mjh was solved by J.L.Thomaston, W.F.Degrado, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.24 / 2.06
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	36.290, 36.150, 76.450, 90.00, 103.60, 90.00
R / Rfree (%)	21.7 / 24.9

The structure of The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Chlorine atom in the The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States (pdb code 6mjh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States, PDB code: 6mjh:

Chlorine binding site 1 out of 1 in the The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The S31N Mutant of the Influenza A M2 Proton Channel in Two Distinct Conformational States within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl101 b:23.4 occ:1.00 OG G:SER23 3.0 18.5 1.0 OG H:SER23 3.1 21.4 1.0 OG F:SER23 3.1 22.7 1.0 OG E:SER23 3.1 17.8 1.0 CB G:SER23 3.4 17.1 1.0 CB H:SER23 3.5 20.2 1.0 CB F:SER23 3.6 17.6 1.0 CB E:SER23 3.6 20.5 1.0 CA G:SER23 4.0 20.6 1.0 CA H:SER23 4.1 20.6 1.0 CA E:SER23 4.2 20.9 1.0 CA F:SER23 4.2 20.4 1.0 CG1 F:VAL27 4.2 22.2 1.0 CG1 G:VAL27 4.2 16.2 1.0 CG1 E:VAL27 4.2 19.3 1.0 CG1 H:VAL27 4.3 22.0 1.0 O G:SER22 4.6 17.8 1.0 O E:SER22 4.6 16.1 1.0 O H:SER22 4.7 18.2 1.0 O F:SER22 4.7 20.6 1.0 CB F:VAL27 4.9 18.9 1.0 CB G:VAL27 4.9 18.6 1.0 N G:ASP24 4.9 21.5 1.0 CB E:VAL27 4.9 18.5 1.0 CB H:VAL27 4.9 18.8 1.0

J.L.Thomaston, Y.Wu, N.Polizzi, L.Liu, J.Wang, W.F.Degrado. X-Ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case. J.Am.Chem.Soc. V. 141 11481 2019.
ISSN: ESSN 1520-5126
PubMed: 31184871
DOI: 10.1021/JACS.9B02196