Chlorine in PDB 6mm6: Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904)

All present enzymatic activity of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904):
2.7.11.11;

The structure of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904), PDB code: 6mm6 was solved by F.Van Petegem, O.Haji-Ghassemi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.87 / 2.39
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	58.451, 74.944, 88.690, 105.51, 90.14, 94.39
R / Rfree (%)	22.4 / 26.1

The binding sites of Chlorine atom in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904) (pdb code 6mm6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904), PDB code: 6mm6:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl404 b:57.1 occ:1.00 O C:GLY200 3.6 28.8 1.0 O D:GLN2808 3.7 61.0 1.0 N C:GLY200 4.3 28.5 1.0 C C:GLY200 4.4 27.9 1.0 CD1 C:LEU205 4.4 28.3 1.0 CG C:LEU198 4.5 33.9 1.0 OH C:TYR247 4.5 36.9 1.0 CD1 C:LEU198 4.5 33.0 1.0 CA C:CYS199 4.5 30.1 1.0 C C:CYS199 4.6 29.0 1.0 C D:GLN2808 4.6 62.3 1.0 CG D:GLN2808 4.7 60.6 1.0 CD2 C:LEU205 4.9 26.6 1.0 O C:LEU198 4.9 32.8 1.0 N C:CYS199 4.9 30.7 1.0 CD2 C:LEU198 5.0 35.6 1.0 CA C:GLY200 5.0 27.6 1.0 CB D:SER2810 5.0 66.3 1.0

Chlorine binding site 2 out of 3 in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl403 b:31.9 occ:1.00 N E:GLU140 3.2 32.1 1.0 CG E:GLU140 3.7 31.3 1.0 CB E:GLU140 3.8 31.5 1.0 CA E:SER139 3.9 33.3 1.0 CD E:PRO141 4.0 33.7 1.0 C E:SER139 4.1 32.1 1.0 CA E:GLU140 4.1 31.2 1.0 CB E:SER139 4.1 34.5 1.0 O E:HOH515 4.2 19.8 1.0 O E:HOH511 4.5 28.6 1.0 CD E:GLU140 4.5 31.5 1.0 OE2 E:GLU140 4.7 31.7 1.0

Chlorine binding site 3 out of 3 in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 Phosphorylation Domain (2699-2904) within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl3001 b:34.2 occ:1.00 NH1 F:ARG2904 3.2 35.2 1.0 NE1 F:TRP2786 3.3 35.8 1.0 CD F:ARG2904 3.5 35.3 1.0 CE F:MET2842 3.7 37.8 1.0 CE2 F:TRP2786 4.0 35.3 1.0 CZ2 F:TRP2786 4.0 35.1 1.0 CZ F:ARG2904 4.2 35.1 1.0 SD F:MET2842 4.3 37.4 1.0 NE F:ARG2904 4.3 35.1 1.0 CD1 F:TRP2786 4.4 36.2 1.0 CB F:ARG2904 4.5 36.0 1.0 CG F:ARG2904 4.6 35.6 1.0

O.Haji-Ghassemi, Z.Yuchi, F.Van Petegem. Camp-Dependent Protein Kinase A in Complex with RYR2 Peptide (2799-2810) Mol.Cell 2019.
ISSN: ISSN 1097-2765