Chlorine in PDB 6mm8: Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2

Enzymatic activity of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2

All present enzymatic activity of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2:
2.7.11.11;

Protein crystallography data

The structure of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2, PDB code: 6mm8 was solved by F.Van Petegem, O.Haji-Ghassemi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.95 / 1.85
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 179.643, 67.860, 58.529, 90.00, 92.22, 90.00
R / Rfree (%) 18.1 / 22.1

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2 (pdb code 6mm8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2, PDB code: 6mm8:

Chlorine binding site 1 out of 1 in 6mm8

Go back to Chlorine Binding Sites List in 6mm8
Chlorine binding site 1 out of 1 in the Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Catalytic Subunit of Camp-Dependent Protein Kinase A in Complex with RYR2 K2879A, S2813D Phosphomimetic (2699-2904) Crystal Form 2 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl3003

b:16.0
occ:1.00
O D:HOH3243 3.2 36.9 1.0
NE1 D:TRP2786 3.2 15.2 1.0
NH1 D:ARG2904 3.3 15.4 1.0
CD D:ARG2904 3.5 14.4 1.0
CE D:MET2842 3.6 21.2 1.0
CE2 D:TRP2786 4.0 14.9 1.0
CZ2 D:TRP2786 4.0 14.9 1.0
CZ D:ARG2904 4.3 14.4 1.0
CD1 D:TRP2786 4.3 14.4 1.0
NE D:ARG2904 4.4 15.1 1.0
SD D:MET2842 4.5 20.9 1.0
CB D:ARG2904 4.5 15.1 1.0
CG D:ARG2904 4.7 14.7 1.0

Reference:

O.Haji-Ghassemi, Z.Yuchi, F.Van Petegem. Camp-Dependent Protein Kinase A in Complex with RYR2 Peptide (2799-2810) Mol.Cell 2019.
ISSN: ISSN 1097-2765
Page generated: Sat Dec 12 13:21:37 2020

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