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Chlorine in PDB 6mob: Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization
Enzymatic activity of Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization
All present enzymatic activity of Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization:
2.7.10.1;
2.7.10.1;
Protein crystallography data
The structure of Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization, PDB code: 6mob
was solved by
T.E.Edwards,
J.Abendroth,
K.Safford,
L.Chun,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 50.00 / 1.80 |
| Space group | P 43 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 80.699, 80.699, 145.020, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18.1 / 21 |
Other elements in 6mob:
The structure of Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization
(pdb code 6mob). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization, PDB code: 6mob:
In total only one binding site of Chlorine was determined in the Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization, PDB code: 6mob:
Chlorine binding site 1 out of 1 in 6mob
Go back to
Chlorine Binding Sites List in 6mob
Chlorine binding site 1 out
of 1 in the Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of KIT1 in Complex with DP2976 Via Co- Crystallization within 5.0Å range:
|
Reference:
B.D.Smith,
M.D.Kaufman,
W.P.Lu,
A.Gupta,
C.B.Leary,
S.C.Wise,
T.J.Rutkoski,
Y.M.Ahn,
G.Al-Ani,
S.L.Bulfer,
T.M.Caldwell,
L.Chun,
C.L.Ensinger,
M.M.Hood,
A.Mckinley,
W.C.Patt,
R.Ruiz-Soto,
Y.Su,
H.Telikepalli,
A.Town,
B.A.Turner,
L.Vogeti,
S.Vogeti,
K.Yates,
F.Janku,
A.R.Abdul Razak,
O.Rosen,
M.C.Heinrich,
D.L.Flynn.
Ripretinib (Dcc-2618) Is A Switch Control Kinase Inhibitor of A Broad Spectrum of Oncogenic and Drug-Resistant Kit and Pdgfra Variants. Cancer Cell V. 35 738 2019.
ISSN: ISSN 1535-6108
PubMed: 31085175
DOI: 10.1016/J.CCELL.2019.04.006
Page generated: Sun Jul 28 03:20:26 2024
ISSN: ISSN 1535-6108
PubMed: 31085175
DOI: 10.1016/J.CCELL.2019.04.006
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