Chlorine in PDB 6mv5: Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K)

The structure of Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K), PDB code: 6mv5 was solved by M.H.Ultsch, D.K.Kirchhofer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.00 / 2.10
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	70.449, 100.420, 86.590, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 23.9

The structure of Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K) also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K) (pdb code 6mv5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K), PDB code: 6mv5:

Chlorine binding site 1 out of 1 in the Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Anti-PCSK9 Fab 6E2 Bound to the N-Terminal Peptide From PCSK9 (E32K) within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl302 b:32.3 occ:1.00 OH P:TYR38 2.8 36.3 1.0 N H:ASN99 3.3 29.4 1.0 N H:VAL98 3.3 28.6 1.0 CA H:GLY94 3.4 31.0 1.0 C H:GLY94 3.4 31.4 1.0 N H:PHE97 3.4 30.7 1.0 N H:ILE96 3.6 30.3 1.0 OD1 H:ASN99 3.6 36.6 1.0 N H:GLU95 3.6 31.0 1.0 CZ P:TYR38 3.7 40.4 1.0 CE1 P:TYR38 3.7 36.3 1.0 N H:GLY94 3.8 30.8 1.0 O H:GLY94 3.9 32.9 1.0 CG1 H:ILE96 3.9 29.6 1.0 CB H:ASN99 3.9 33.4 1.0 C H:ILE96 4.0 33.8 1.0 CA H:VAL98 4.0 26.4 1.0 CB H:VAL98 4.0 27.6 1.0 CA H:ASN99 4.1 29.1 1.0 CA H:PHE97 4.1 29.5 1.0 C H:VAL98 4.1 29.5 1.0 CG H:ASN99 4.1 33.7 1.0 C H:PHE97 4.2 30.1 1.0 CA H:ILE96 4.2 32.4 1.0 O H:ASN99 4.3 30.6 1.0 C H:GLU95 4.5 32.1 1.0 CA H:GLU95 4.6 31.8 1.0 C H:ASN99 4.7 28.6 1.0 CG2 H:VAL98 4.7 26.9 1.0 CB H:ILE96 4.7 29.7 1.0 O H:ILE96 4.7 30.8 1.0 CE2 P:TYR38 5.0 39.2 1.0 CD1 H:ILE96 5.0 30.9 1.0

M.Ultsch, W.Li, C.Eigenbrot, P.Di Lello, M.T.Lipari, S.Gerhardy, A.P.Ahyoung, J.Quinn, Y.Franke, Y.Chen, M.Kong Beltran, A.Peterson, D.Kirchhofer. Identification of A Helical Segment Within the Intrinsically Disordered Region of the PCSK9 Prodomain. J. Mol. Biol. V. 431 885 2019.
ISSN: ESSN 1089-8638
PubMed: 30653992
DOI: 10.1016/J.JMB.2018.11.025