Chlorine in PDB 6n67: Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1

All present enzymatic activity of Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1:
6.5.1.3;

The structure of Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1, PDB code: 6n67 was solved by J.Peschek, P.Walter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.74 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.729, 56.580, 173.879, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21.4

The binding sites of Chlorine atom in the Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1 (pdb code 6n67). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1, PDB code: 6n67:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:51.3 occ:1.00 O A:HOH801 2.9 56.4 1.0 O A:HOH608 2.9 52.0 1.0 O A:HOH710 3.2 33.3 1.0 N A:ILE153 3.4 28.8 1.0 CA A:CYS152 3.8 31.3 1.0 CG2 A:ILE153 3.9 36.7 1.0 CB A:CYS152 3.9 32.4 1.0 O1G A:APC501 4.0 85.8 1.0 O A:HOH862 4.0 57.5 1.0 CE A:LYS169 4.1 58.6 1.0 O A:HOH624 4.1 42.8 1.0 O3G A:APC501 4.1 91.0 1.0 C A:CYS152 4.1 32.9 1.0 CB A:ILE153 4.3 31.4 1.0 CB A:LYS169 4.4 44.8 1.0 CA A:ILE153 4.4 29.6 1.0 CD A:LYS169 4.5 55.6 1.0 O A:HOH835 4.6 46.2 1.0 NZ A:LYS169 4.7 67.2 1.0 PG A:APC501 4.7 95.2 1.0 O2' A:APC501 4.8 31.5 1.0 O A:ILE153 4.8 28.5 1.0 O A:GLY151 4.9 36.0 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl505 b:77.4 occ:1.00 NE A:ARG209 3.3 61.2 1.0 NH2 A:ARG209 3.5 59.0 1.0 O A:HOH666 3.6 50.3 1.0 O A:HOH848 3.6 55.1 1.0 CZ A:ARG209 3.9 59.0 1.0 CG A:ARG209 4.3 45.2 1.0 CD A:ARG209 4.3 52.0 1.0 C3 A:GOL509 4.5 61.0 1.0 C2 A:GOL509 4.9 65.1 1.0 O2 A:GOL509 5.0 68.6 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Ligase Domain of Fungal Trna Ligase TRL1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl506 b:70.6 occ:1.00 OH A:TYR33 3.3 44.0 1.0 CE2 A:TYR33 3.8 35.9 1.0 CZ A:TYR33 4.0 37.0 1.0 CB A:SER35 4.1 40.9 1.0 OG A:SER35 4.6 44.3 1.0 O A:HOH871 4.6 62.3 1.0 O A:HOH631 5.0 48.0 1.0

J.Peschek, P.Walter. Trna Ligase Structure Reveals Kinetic Competition Between Non-Conventional Mrna Splicing and Mrna Decay. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 31237564
DOI: 10.7554/ELIFE.44199