Chlorine in PDB 6nsv: Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide

Enzymatic activity of Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide

All present enzymatic activity of Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide:
2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide, PDB code: 6nsv was solved by K.Basu, M.Ravalin, M.-F.Bohn, C.S.Craik, J.E.Gestwicki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.74 / 1.31
Space group P 2 21 21
Cell size a, b, c (Å), α, β, γ (°) 46.219, 71.920, 77.790, 90.00, 90.00, 90.00
R / Rfree (%) 21.4 / 24.3

Other elements in 6nsv:

The structure of Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide also contains other interesting chemical elements:

Sodium (Na) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide (pdb code 6nsv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide, PDB code: 6nsv:

Chlorine binding site 1 out of 1 in 6nsv

Go back to Chlorine Binding Sites List in 6nsv
Chlorine binding site 1 out of 1 in the Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human Chip Tpr Domain in Complex with A 5MER Acetylated Optimized Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl201

b:58.2
occ:1.00
 H162 A:1PE203 2.7 50.4 1.0
H262 A:1PE203 3.0 27.2 1.0
HZ2 A:LYS72 3.2 24.2 1.0
C16 A:1PE203 3.4 42.0 1.0
H261 A:1PE203 3.4 27.2 1.0
C26 A:1PE203 3.4 22.7 1.0
O A:HOH317 3.6 27.5 1.0
HZ3 A:LYS72 3.6 24.2 1.0
HE2 A:LYS72 3.6 22.7 1.0
NZ A:LYS72 3.8 20.2 1.0
H161 A:1PE203 3.9 50.4 1.0
OH A:TYR42 3.9 22.3 1.0
HE1 A:PHE37 4.0 19.2 1.0
H121 A:1PE203 4.1 43.5 1.0
HH A:TYR42 4.1 26.8 1.0
CE A:LYS72 4.2 18.9 1.0
HH2 C:TRP639 4.3 36.2 1.0
CH2 C:TRP639 4.4 30.2 1.0
HO7 A:1PE203 4.4 63.1 1.0
OH7 A:1PE203 4.5 52.6 1.0
O A:HOH391 4.5 34.5 1.0
OH2 A:1PE203 4.5 44.3 1.0
HZ A:PHE37 4.5 18.5 1.0
HD3 A:LYS72 4.6 28.0 1.0
HZ1 A:LYS72 4.6 24.2 1.0
CZ2 C:TRP639 4.6 35.6 1.0
CE1 A:PHE37 4.6 16.1 1.0
H221 A:1PE203 4.6 39.0 1.0
H162 B:1PE202 4.7 33.4 1.0
HZ2 C:TRP639 4.7 42.8 1.0
C12 A:1PE203 4.7 36.2 1.0
CZ3 C:TRP639 4.8 38.5 1.0
OH6 A:1PE203 4.8 33.0 1.0
H151 A:1PE203 4.9 28.4 1.0
CZ A:PHE37 4.9 15.4 1.0
HE3 A:LYS72 5.0 22.7 1.0
HZ3 C:TRP639 5.0 46.2 1.0
CD A:LYS72 5.0 23.3 1.0

Reference:

M.Ravalin, P.Theofilas, K.Basu, K.A.Opoku-Nsiah, V.A.Assimon, D.Medina-Cleghorn, Y.F.Chen, M.F.Bohn, M.Arkin, L.T.Grinberg, C.S.Craik, J.E.Gestwicki. Specificity For Latent C Termini Links the E3 Ubiquitin Ligase Chip to Caspases. Nat.Chem.Biol. V. 15 786 2019.
ISSN: ESSN 1552-4469
PubMed: 31320752
DOI: 10.1038/S41589-019-0322-6
Page generated: Sat Dec 12 13:24:48 2020

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