Chlorine in PDB 6nzw: LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State

The binding sites of Chlorine atom in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State (pdb code 6nzw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State, PDB code: 6nzw:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl904 b:69.8 occ:1.00 CL12 A:L9Y904 0.0 69.8 1.0 C11 A:L9Y904 1.7 69.8 1.0 C08 A:L9Y904 2.6 69.8 1.0 C13 A:L9Y904 2.7 69.8 1.0 CL14 A:L9Y904 2.9 69.8 1.0 O10 A:L9Y904 3.0 69.8 1.0 C09 A:L9Y904 3.1 69.8 1.0 HB2 F:ARG103 3.7 57.0 1.0 H272 A:L9Y904 3.8 69.8 1.0 H252 A:L9Y904 3.8 69.8 1.0 C07 A:L9Y904 4.0 69.8 1.0 H262 A:L9Y904 4.0 69.8 1.0 C15 A:L9Y904 4.0 69.8 1.0 HB2 A:ARG103 4.2 57.9 1.0 H F:ARG103 4.2 57.0 1.0 H012 A:L9Y904 4.3 69.8 1.0 HB3 F:ARG103 4.4 57.0 1.0 CB F:ARG103 4.5 57.0 1.0 C23 A:L9Y904 4.5 69.8 1.0 C25 A:L9Y904 4.5 69.8 1.0 C26 A:L9Y904 4.5 69.8 1.0 C05 A:L9Y904 4.5 69.8 1.0 C27 A:L9Y904 4.5 69.8 1.0 HD2 F:ARG103 4.9 57.0 1.0 N F:ARG103 4.9 57.0 1.0 C06 A:L9Y904 4.9 69.8 1.0 C24 A:L9Y904 4.9 69.8 1.0 HB2 F:ASP102 5.0 57.2 1.0

Chlorine binding site 2 out of 2 in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of LRRC8A-Dcpib in MSP1E3D1 Nanodisc Constricted State within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl904 b:69.8 occ:1.00 CL14 A:L9Y904 0.0 69.8 1.0 C13 A:L9Y904 1.7 69.8 1.0 C11 A:L9Y904 2.6 69.8 1.0 HD2 A:ARG103 2.7 57.9 1.0 HD2 F:ARG103 2.7 57.0 1.0 C15 A:L9Y904 2.8 69.8 1.0 CL12 A:L9Y904 2.9 69.8 1.0 HD3 F:ARG103 3.0 57.0 1.0 O16 A:L9Y904 3.2 69.8 1.0 HG3 A:ARG103 3.2 57.9 1.0 CD F:ARG103 3.3 57.0 1.0 HH11 F:ARG103 3.4 57.0 1.0 HB2 F:ARG103 3.4 57.0 1.0 HB2 A:ARG103 3.4 57.9 1.0 HB3 F:ARG103 3.4 57.0 1.0 CD A:ARG103 3.5 57.9 1.0 CG A:ARG103 3.7 57.9 1.0 CB F:ARG103 3.8 57.0 1.0 C08 A:L9Y904 3.9 69.8 1.0 C23 A:L9Y904 4.0 69.8 1.0 CB A:ARG103 4.0 57.9 1.0 CG F:ARG103 4.0 57.0 1.0 NH1 F:ARG103 4.2 57.0 1.0 HD3 A:ARG103 4.2 57.9 1.0 NE A:ARG103 4.3 57.9 1.0 H172 A:L9Y904 4.3 69.8 1.0 HE A:ARG103 4.3 57.9 1.0 C17 A:L9Y904 4.3 69.8 1.0 HG3 F:ARG103 4.3 57.0 1.0 H272 A:L9Y904 4.4 69.8 1.0 NE F:ARG103 4.4 57.0 1.0 C07 A:L9Y904 4.5 69.8 1.0 HB3 A:ARG103 4.5 57.9 1.0 HG2 A:ARG103 4.6 57.9 1.0 H181 A:L9Y904 4.6 69.8 1.0 HH11 A:ARG103 4.7 57.9 1.0 H231 A:L9Y904 4.8 69.8 1.0 HH12 F:ARG103 4.8 57.0 1.0 CZ F:ARG103 4.8 57.0 1.0 HG2 F:ARG103 4.9 57.0 1.0 H F:ARG103 4.9 57.0 1.0 CZ A:ARG103 5.0 57.9 1.0

D.M.Kern, S.Oh, R.K.Hite, S.G.Brohawn. Cryo-Em Structures of the Dcpib-Inhibited Volume-Regulated Anion Channel LRRC8A in Lipid Nanodiscs. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 30775971
DOI: 10.7554/ELIFE.42636