Chlorine in PDB 6nzz: LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State

The binding sites of Chlorine atom in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State (pdb code 6nzz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State, PDB code: 6nzz:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl904 b:38.7 occ:1.00 CL12 F:L9Y904 0.0 38.7 1.0 C11 F:L9Y904 1.7 38.7 1.0 C08 F:L9Y904 2.7 38.7 1.0 C13 F:L9Y904 2.7 38.7 1.0 H262 F:L9Y904 3.0 38.7 1.0 CL14 F:L9Y904 3.0 38.7 1.0 O10 F:L9Y904 3.1 38.7 1.0 C09 F:L9Y904 3.2 38.7 1.0 H251 F:L9Y904 3.8 38.7 1.0 C26 F:L9Y904 3.9 38.7 1.0 C07 F:L9Y904 4.0 38.7 1.0 C15 F:L9Y904 4.0 38.7 1.0 HB2 F:ARG103 4.1 27.2 1.0 H271 F:L9Y904 4.1 38.7 1.0 C25 F:L9Y904 4.3 38.7 1.0 H261 F:L9Y904 4.5 38.7 1.0 C23 F:L9Y904 4.5 38.7 1.0 C27 F:L9Y904 4.6 38.7 1.0 C05 F:L9Y904 4.6 38.7 1.0 H F:ARG103 4.7 27.2 1.0 H021 F:L9Y904 4.8 38.7 1.0 C24 F:L9Y904 4.9 38.7 1.0 C06 F:L9Y904 5.0 38.7 1.0

Chlorine binding site 2 out of 2 in the LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of LRRC8A-Dcpib in MSP1E3D1 Nanodisc Expanded State within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl904 b:38.7 occ:1.00 CL14 F:L9Y904 0.0 38.7 1.0 C13 F:L9Y904 1.7 38.7 1.0 C11 F:L9Y904 2.6 38.7 1.0 C15 F:L9Y904 2.7 38.7 1.0 HD2 F:ARG103 2.7 27.2 1.0 HB2 F:ARG103 2.8 27.2 1.0 CL12 F:L9Y904 3.0 38.7 1.0 O16 F:L9Y904 3.1 38.7 1.0 HD3 F:ARG103 3.2 27.2 1.0 CD F:ARG103 3.3 27.2 1.0 HB3 F:ARG103 3.4 27.2 1.0 CB F:ARG103 3.5 27.2 1.0 HD2 A:ARG103 3.5 27.1 1.0 CG F:ARG103 3.9 27.2 1.0 C08 F:L9Y904 3.9 38.7 1.0 HH11 F:ARG103 4.0 27.2 1.0 HB2 A:ARG103 4.0 27.1 1.0 C23 F:L9Y904 4.0 38.7 1.0 HG3 A:ARG103 4.0 27.1 1.0 HG3 F:ARG103 4.1 27.2 1.0 C17 F:L9Y904 4.3 38.7 1.0 H271 F:L9Y904 4.3 38.7 1.0 CD A:ARG103 4.4 27.1 1.0 H262 F:L9Y904 4.4 38.7 1.0 H181 F:L9Y904 4.4 38.7 1.0 H172 F:L9Y904 4.4 38.7 1.0 H F:ARG103 4.5 27.2 1.0 C07 F:L9Y904 4.5 38.7 1.0 CG A:ARG103 4.6 27.1 1.0 NE F:ARG103 4.6 27.2 1.0 H231 F:L9Y904 4.7 38.7 1.0 NH1 F:ARG103 4.7 27.2 1.0 CB A:ARG103 4.7 27.1 1.0 HG2 F:ARG103 4.8 27.2 1.0 CA F:ARG103 4.8 27.2 1.0 C18 F:L9Y904 4.9 38.7 1.0 N F:ARG103 5.0 27.2 1.0 HD3 A:ARG103 5.0 27.1 1.0

D.M.Kern, S.Oh, R.K.Hite, S.G.Brohawn. Cryo-Em Structures of the Dcpib-Inhibited Volume-Regulated Anion Channel LRRC8A in Lipid Nanodiscs. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 30775971
DOI: 10.7554/ELIFE.42636