Chlorine in PDB 6o81: Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
(pdb code 6o81). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the
Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens, PDB code: 6o81:
Jump to Chlorine binding site number:
1;
2;
3;
4;
Chlorine binding site 1 out
of 4 in 6o81
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Chlorine Binding Sites List in 6o81
Chlorine binding site 1 out
of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
Mono view
Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl401
b:60.9
occ:0.50
|
CL1
|
C:C7B401
|
0.0
|
60.9
|
0.5
|
CL2
|
C:C7B401
|
0.4
|
60.9
|
0.5
|
C29
|
C:C7B401
|
1.8
|
60.9
|
0.5
|
C30
|
C:C7B401
|
2.0
|
60.9
|
0.5
|
C27
|
C:C7B401
|
2.7
|
60.9
|
0.5
|
C25
|
C:C7B401
|
2.8
|
60.9
|
0.5
|
C28
|
C:C7B401
|
2.9
|
60.9
|
0.5
|
C26
|
C:C7B401
|
3.1
|
60.9
|
0.5
|
CG2
|
D:VAL225
|
3.6
|
51.8
|
1.0
|
CD2
|
E:LEU485
|
3.6
|
63.0
|
1.0
|
CG2
|
D:THR215
|
4.0
|
57.8
|
1.0
|
C23
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
C21
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
CD1
|
D:ILE190
|
4.1
|
54.6
|
1.0
|
C24
|
C:C7B401
|
4.2
|
60.9
|
0.5
|
C22
|
C:C7B401
|
4.3
|
60.9
|
0.5
|
CE1
|
E:PHE180
|
4.4
|
63.2
|
1.0
|
CG1
|
E:VAL177
|
4.4
|
64.0
|
1.0
|
C19
|
C:C7B401
|
4.6
|
60.9
|
0.5
|
C20
|
C:C7B401
|
4.8
|
60.9
|
0.5
|
CG1
|
D:ILE190
|
4.8
|
54.6
|
1.0
|
CB
|
D:VAL225
|
4.8
|
51.8
|
1.0
|
CB
|
D:THR215
|
4.8
|
57.8
|
1.0
|
CE2
|
E:PHE452
|
4.8
|
59.2
|
1.0
|
CG2
|
D:ILE190
|
5.0
|
54.6
|
1.0
|
|
Chlorine binding site 2 out
of 4 in 6o81
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Chlorine Binding Sites List in 6o81
Chlorine binding site 2 out
of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
Mono view
Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl401
b:60.9
occ:0.50
|
CL1
|
C:C7B401
|
0.0
|
60.9
|
0.5
|
CL2
|
C:C7B401
|
0.7
|
60.9
|
0.5
|
C29
|
C:C7B401
|
1.8
|
60.9
|
0.5
|
C30
|
C:C7B401
|
2.2
|
60.9
|
0.5
|
C27
|
C:C7B401
|
2.7
|
60.9
|
0.5
|
C25
|
C:C7B401
|
2.8
|
60.9
|
0.5
|
C28
|
C:C7B401
|
2.9
|
60.9
|
0.5
|
C26
|
C:C7B401
|
3.3
|
60.9
|
0.5
|
CG2
|
C:VAL225
|
3.6
|
51.9
|
1.0
|
CD2
|
F:LEU485
|
3.6
|
62.9
|
1.0
|
C23
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
C21
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
CD1
|
C:ILE190
|
4.2
|
53.9
|
1.0
|
CE2
|
F:PHE180
|
4.2
|
63.2
|
1.0
|
C24
|
C:C7B401
|
4.3
|
60.9
|
0.5
|
OG1
|
C:THR215
|
4.4
|
56.8
|
1.0
|
C22
|
C:C7B401
|
4.5
|
60.9
|
0.5
|
CG1
|
F:VAL177
|
4.5
|
64.2
|
1.0
|
C19
|
C:C7B401
|
4.6
|
60.9
|
0.5
|
SD
|
C:MET217
|
4.6
|
63.8
|
1.0
|
CG1
|
C:ILE190
|
4.8
|
53.9
|
1.0
|
CB
|
C:VAL225
|
4.8
|
51.9
|
1.0
|
CE2
|
F:PHE452
|
4.8
|
60.6
|
1.0
|
CZ
|
F:PHE452
|
4.9
|
60.6
|
1.0
|
CD2
|
F:PHE180
|
4.9
|
63.2
|
1.0
|
C20
|
C:C7B401
|
4.9
|
60.9
|
0.5
|
|
Chlorine binding site 3 out
of 4 in 6o81
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Chlorine Binding Sites List in 6o81
Chlorine binding site 3 out
of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
Mono view
Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl401
b:60.9
occ:0.50
|
CL2
|
C:C7B401
|
0.0
|
60.9
|
0.5
|
CL1
|
C:C7B401
|
0.7
|
60.9
|
0.5
|
C29
|
C:C7B401
|
1.4
|
60.9
|
0.5
|
C30
|
C:C7B401
|
1.8
|
60.9
|
0.5
|
C25
|
C:C7B401
|
2.2
|
60.9
|
0.5
|
C27
|
C:C7B401
|
2.6
|
60.9
|
0.5
|
C28
|
C:C7B401
|
2.7
|
60.9
|
0.5
|
C26
|
C:C7B401
|
2.8
|
60.9
|
0.5
|
C21
|
C:C7B401
|
3.5
|
60.9
|
0.5
|
CG2
|
C:VAL225
|
3.5
|
51.9
|
1.0
|
C23
|
C:C7B401
|
3.8
|
60.9
|
0.5
|
CD2
|
F:LEU485
|
3.9
|
62.9
|
1.0
|
CE2
|
F:PHE180
|
4.0
|
63.2
|
1.0
|
C24
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
C22
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
C19
|
C:C7B401
|
4.1
|
60.9
|
0.5
|
CD1
|
C:ILE190
|
4.2
|
53.9
|
1.0
|
CE2
|
F:PHE452
|
4.3
|
60.6
|
1.0
|
CG1
|
F:VAL177
|
4.4
|
64.2
|
1.0
|
CZ
|
F:PHE452
|
4.4
|
60.6
|
1.0
|
C20
|
C:C7B401
|
4.5
|
60.9
|
0.5
|
CD2
|
F:PHE180
|
4.7
|
63.2
|
1.0
|
OG1
|
C:THR215
|
4.7
|
56.8
|
1.0
|
CB
|
C:VAL225
|
4.9
|
51.9
|
1.0
|
CG1
|
C:ILE190
|
4.9
|
53.9
|
1.0
|
CB
|
F:LEU179
|
5.0
|
61.7
|
1.0
|
CZ
|
F:PHE180
|
5.0
|
63.2
|
1.0
|
|
Chlorine binding site 4 out
of 4 in 6o81
Go back to
Chlorine Binding Sites List in 6o81
Chlorine binding site 4 out
of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens
Mono view
Stereo pair view
|
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Cl401
b:60.9
occ:0.50
|
CL2
|
C:C7B401
|
0.0
|
60.9
|
0.5
|
CL1
|
C:C7B401
|
0.4
|
60.9
|
0.5
|
C29
|
C:C7B401
|
1.6
|
60.9
|
0.5
|
C30
|
C:C7B401
|
1.8
|
60.9
|
0.5
|
C25
|
C:C7B401
|
2.4
|
60.9
|
0.5
|
C27
|
C:C7B401
|
2.7
|
60.9
|
0.5
|
C28
|
C:C7B401
|
2.7
|
60.9
|
0.5
|
C26
|
C:C7B401
|
2.8
|
60.9
|
0.5
|
CG2
|
D:VAL225
|
3.6
|
51.8
|
1.0
|
C21
|
C:C7B401
|
3.7
|
60.9
|
0.5
|
CD2
|
E:LEU485
|
3.8
|
63.0
|
1.0
|
C23
|
C:C7B401
|
3.9
|
60.9
|
0.5
|
C24
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
C22
|
C:C7B401
|
4.0
|
60.9
|
0.5
|
CE1
|
E:PHE180
|
4.1
|
63.2
|
1.0
|
CD1
|
D:ILE190
|
4.2
|
54.6
|
1.0
|
CG2
|
D:THR215
|
4.3
|
57.8
|
1.0
|
CG1
|
E:VAL177
|
4.3
|
64.0
|
1.0
|
C19
|
C:C7B401
|
4.3
|
60.9
|
0.5
|
CE2
|
E:PHE452
|
4.5
|
59.2
|
1.0
|
C20
|
C:C7B401
|
4.5
|
60.9
|
0.5
|
CD1
|
E:PHE180
|
4.8
|
63.2
|
1.0
|
CB
|
D:VAL225
|
4.9
|
51.8
|
1.0
|
CZ
|
E:PHE452
|
5.0
|
59.2
|
1.0
|
CG1
|
D:ILE190
|
5.0
|
54.6
|
1.0
|
|
Reference:
L.R.Kenner,
A.A.Anand,
H.C.Nguyen,
A.G.Myasnikov,
C.J.Klose,
L.A.Mcgeever,
J.C.Tsai,
L.E.Miller-Vedam,
P.Walter,
A.Frost.
EIF2B-Catalyzed Nucleotide Exchange and Phosphoregulation By the Integrated Stress Response. Science V. 364 491 2019.
ISSN: ESSN 1095-9203
PubMed: 31048491
DOI: 10.1126/SCIENCE.AAW2922
Page generated: Mon Jul 29 12:33:30 2024
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