Chlorine in PDB 6o85: Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens

The binding sites of Chlorine atom in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens (pdb code 6o85). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens, PDB code: 6o85:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:38.8 occ:0.50 CL1 C:C7B401 0.0 38.8 0.5 CL2 C:C7B401 0.5 38.8 0.5 C29 C:C7B401 1.8 38.8 0.5 C30 C:C7B401 2.1 38.8 0.5 C27 C:C7B401 2.7 38.8 0.5 C25 C:C7B401 2.8 38.8 0.5 C28 C:C7B401 2.9 38.8 0.5 C26 C:C7B401 3.1 38.8 0.5 CG1 D:VAL225 3.6 33.8 1.0 CD2 E:LEU485 3.6 42.8 1.0 CG2 D:THR215 3.8 39.5 1.0 C23 C:C7B401 4.0 38.8 0.5 C21 C:C7B401 4.0 38.8 0.5 CD1 D:ILE190 4.2 35.2 1.0 C24 C:C7B401 4.2 38.8 0.5 CG2 D:VAL225 4.3 33.8 1.0 C22 C:C7B401 4.4 38.8 0.5 CG1 E:VAL177 4.5 41.7 1.0 CB D:THR215 4.5 39.5 1.0 C19 C:C7B401 4.5 38.8 0.5 CB D:VAL225 4.6 33.8 1.0 CE2 E:PHE180 4.7 40.3 1.0 CG2 D:ILE190 4.7 35.2 1.0 OG1 D:THR215 4.8 39.5 1.0 C20 C:C7B401 4.8 38.8 0.5 CE2 E:PHE452 4.9 38.3 1.0 CG1 D:ILE190 4.9 35.2 1.0 SD D:MET217 4.9 40.5 1.0

Chlorine binding site 2 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:38.8 occ:0.50 CL1 C:C7B401 0.0 38.8 0.5 CL2 C:C7B401 0.4 38.8 0.5 C29 C:C7B401 1.8 38.8 0.5 C30 C:C7B401 2.1 38.8 0.5 C25 C:C7B401 2.7 38.8 0.5 C27 C:C7B401 2.8 38.8 0.5 C28 C:C7B401 3.0 38.8 0.5 C26 C:C7B401 3.1 38.8 0.5 CD2 F:LEU485 3.6 40.2 1.0 CG1 C:VAL225 3.8 30.1 1.0 C21 C:C7B401 4.0 38.8 0.5 C23 C:C7B401 4.0 38.8 0.5 CG2 C:THR215 4.2 39.6 1.0 CD1 C:ILE190 4.2 35.9 1.0 C24 C:C7B401 4.3 38.8 0.5 C22 C:C7B401 4.4 38.8 0.5 CE2 F:PHE180 4.4 37.2 1.0 CB C:VAL225 4.4 30.1 1.0 CG1 F:VAL177 4.5 39.9 1.0 C19 C:C7B401 4.6 38.8 0.5 CE2 F:PHE452 4.7 34.4 1.0 CG2 C:ILE190 4.8 35.9 1.0 C20 C:C7B401 4.9 38.8 0.5 CZ F:PHE452 5.0 34.4 1.0

Chlorine binding site 3 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:38.8 occ:0.50 CL2 C:C7B401 0.0 38.8 0.5 CL1 C:C7B401 0.4 38.8 0.5 C29 C:C7B401 1.5 38.8 0.5 C30 C:C7B401 1.8 38.8 0.5 C25 C:C7B401 2.4 38.8 0.5 C27 C:C7B401 2.5 38.8 0.5 C28 C:C7B401 2.8 38.8 0.5 C26 C:C7B401 2.8 38.8 0.5 C21 C:C7B401 3.7 38.8 0.5 C23 C:C7B401 3.8 38.8 0.5 CD2 F:LEU485 3.8 40.2 1.0 C24 C:C7B401 4.0 38.8 0.5 C22 C:C7B401 4.0 38.8 0.5 CG1 C:VAL225 4.0 30.1 1.0 C19 C:C7B401 4.2 38.8 0.5 CD1 C:ILE190 4.2 35.9 1.0 CE2 F:PHE180 4.3 37.2 1.0 CG1 F:VAL177 4.3 39.9 1.0 CG2 C:THR215 4.3 39.6 1.0 CE2 F:PHE452 4.5 34.4 1.0 C20 C:C7B401 4.6 38.8 0.5 CB C:VAL225 4.6 30.1 1.0 CZ F:PHE452 4.9 34.4 1.0 CD2 F:PHE180 4.9 37.2 1.0 CG2 C:ILE190 5.0 35.9 1.0

Chlorine binding site 4 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B Bound to Eukaryotic Translation Initiation Factor 2 From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:38.8 occ:0.50 CL2 C:C7B401 0.0 38.8 0.5 CL1 C:C7B401 0.5 38.8 0.5 C29 C:C7B401 1.5 38.8 0.5 C30 C:C7B401 1.8 38.8 0.5 C25 C:C7B401 2.4 38.8 0.5 C27 C:C7B401 2.6 38.8 0.5 C28 C:C7B401 2.7 38.8 0.5 C26 C:C7B401 2.8 38.8 0.5 CG1 D:VAL225 3.6 33.8 1.0 CD2 E:LEU485 3.7 42.8 1.0 C21 C:C7B401 3.7 38.8 0.5 C23 C:C7B401 3.8 38.8 0.5 C24 C:C7B401 4.0 38.8 0.5 C22 C:C7B401 4.0 38.8 0.5 CG2 D:THR215 4.1 39.5 1.0 CG1 E:VAL177 4.2 41.7 1.0 CD1 D:ILE190 4.2 35.2 1.0 C19 C:C7B401 4.3 38.8 0.5 CG2 D:VAL225 4.4 33.8 1.0 CE2 E:PHE180 4.4 40.3 1.0 CE2 E:PHE452 4.5 38.3 1.0 C20 C:C7B401 4.5 38.8 0.5 CB D:VAL225 4.7 33.8 1.0 CB D:THR215 4.8 39.5 1.0 OG1 D:THR215 4.9 39.5 1.0 CD2 E:PHE180 5.0 40.3 1.0 CZ E:PHE452 5.0 38.3 1.0

L.R.Kenner, A.A.Anand, H.C.Nguyen, A.G.Myasnikov, C.J.Klose, L.A.Mcgeever, J.C.Tsai, L.E.Miller-Vedam, P.Walter, A.Frost. EIF2B-Catalyzed Nucleotide Exchange and Phosphoregulation By the Integrated Stress Response. Science V. 364 491 2019.
ISSN: ESSN 1095-9203
PubMed: 31048491
DOI: 10.1126/SCIENCE.AAW2922