Chlorine in PDB 6ob2: Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1)

The structure of Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1), PDB code: 6ob2 was solved by T.H.Tran, S.Dharmaiah, D.K.Simanshu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.00 / 2.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	83.728, 99.736, 155.514, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 24.7

The structure of Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1) also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1) (pdb code 6ob2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1), PDB code: 6ob2:

Chlorine binding site 1 out of 1 in the Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Wild-Type Kras (Gmppnp-Bound) in Complex with Gap-Related Domain (Grd) of Neurofibromin (NF1) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1503 b:85.2 occ:1.00 ND2 B:ASN1259 4.4 93.7 1.0 CB B:MET1225 4.7 63.0 1.0 CE B:LYS1263 4.8 89.9 1.0 CG B:MET1225 4.9 67.6 1.0 CA B:PRO1222 5.0 73.6 1.0

D.Rabara, T.H.Tran, S.Dharmaiah, R.M.Stephens, F.Mccormick, D.K.Simanshu, M.Holderfield. Kras G13D Sensitivity to Neurofibromin-Mediated Gtp Hydrolysis. Proc.Natl.Acad.Sci.Usa V. 116 22122 2019.
ISSN: ESSN 1091-6490
PubMed: 31611389
DOI: 10.1073/PNAS.1908353116