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Chlorine in PDB 6oco: Human PI3KDELTA in Complex with Compound 6Enzymatic activity of Human PI3KDELTA in Complex with Compound 6
All present enzymatic activity of Human PI3KDELTA in Complex with Compound 6:
2.7.1.153; Protein crystallography data
The structure of Human PI3KDELTA in Complex with Compound 6, PDB code: 6oco
was solved by
C.A.Lesburg,
M.A.Augustin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human PI3KDELTA in Complex with Compound 6
(pdb code 6oco). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human PI3KDELTA in Complex with Compound 6, PDB code: 6oco: Chlorine binding site 1 out of 1 in 6ocoGo back to Chlorine Binding Sites List in 6oco
Chlorine binding site 1 out
of 1 in the Human PI3KDELTA in Complex with Compound 6
Mono view Stereo pair view
Reference:
H.Zhou,
M.A.Mcgowan,
K.Lipford,
M.Christopher,
X.Fradera,
D.Witter,
C.A.Lesburg,
C.Li,
J.L.Methot,
J.Lampe,
A.Achab,
L.Shaffer,
P.Goldenblatt,
S.Shah,
A.Bass,
G.Schroeder,
D.Chen,
H.Zeng,
M.A.Augustin,
J.D.Katz.
Discovery and Optimization of Heteroaryl Piperazines As Potent and Selective PI3K Delta Inhibitors. Bioorg.Med.Chem.Lett. V. 30 26715 2020.
Page generated: Sat Dec 12 13:26:48 2020
ISSN: ESSN 1464-3405 PubMed: 31757666 DOI: 10.1016/J.BMCL.2019.126715 |
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