Chlorine in PDB 6ol7: Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv

The structure of Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv, PDB code: 6ol7 was solved by C.Weidle, M.Pancera, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.78 / 2.42
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	51.583, 107.937, 116.961, 85.49, 80.28, 84.17
R / Rfree (%)	17.4 / 22.4

The binding sites of Chlorine atom in the Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv (pdb code 6ol7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv, PDB code: 6ol7:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv within 5.0Å range: probe atom residue distance (Å) B Occ K:Cl206 b:41.8 occ:1.00 H K:TYR97 2.5 32.6 1.0 O K:HOH354 3.1 32.1 1.0 HH F:TYR32 3.2 23.2 1.0 N K:TYR97 3.3 27.1 1.0 HG23 K:THR96 3.4 28.9 1.0 HA K:TYR97 3.7 35.6 1.0 HA K:THR96 3.7 34.3 1.0 OH F:TYR32 3.8 19.3 1.0 CA K:TYR97 4.0 29.6 1.0 CD1 K:TYR97 4.1 21.7 1.0 CG K:TYR97 4.2 25.0 1.0 C K:THR96 4.2 24.2 1.0 O K:HOH310 4.3 23.2 1.0 CE1 K:TYR97 4.3 22.3 1.0 CG2 K:THR96 4.3 24.0 1.0 HD1 K:TYR97 4.4 26.0 1.0 CD2 K:TYR97 4.4 27.1 1.0 CA K:THR96 4.4 28.6 1.0 O F:HOH328 4.4 20.3 1.0 HG22 K:THR96 4.4 28.9 1.0 CZ K:TYR97 4.5 23.1 1.0 CE2 K:TYR97 4.5 21.2 1.0 HE1 K:TYR97 4.7 26.8 1.0 CB K:TYR97 4.7 24.8 1.0 HE2 F:TYR32 4.7 34.4 1.0 HD2 K:TYR97 4.8 32.6 1.0 HB3 I:ASP99 4.9 48.5 1.0 CZ F:TYR32 4.9 27.0 1.0 O K:HOH316 4.9 26.6 1.0 CB K:THR96 5.0 29.8 1.0 HG21 K:THR96 5.0 28.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of GLVRC01 Scfv in Complex with Anti-Idiotype IV8 Scfv within 5.0Å range: probe atom residue distance (Å) B Occ P:Cl201 b:51.5 occ:1.00 H P:TYR97 2.8 45.6 1.0 HH N:TYR32 3.3 26.5 1.0 HG23 P:THR96 3.5 41.0 1.0 N P:TYR97 3.5 38.0 1.0 O P:HOH361 3.8 28.9 1.0 HA P:TYR97 3.8 38.5 1.0 OH N:TYR32 3.9 22.1 1.0 HA P:THR96 4.0 36.0 1.0 CD1 P:TYR97 4.0 35.9 1.0 CG P:TYR97 4.0 40.4 1.0 CE1 P:TYR97 4.1 39.6 1.0 CD2 P:TYR97 4.1 29.8 1.0 CZ P:TYR97 4.1 37.6 1.0 CA P:TYR97 4.2 32.1 1.0 CE2 P:TYR97 4.2 31.7 1.0 HD1 P:TYR97 4.4 43.1 1.0 CG2 P:THR96 4.4 34.2 1.0 C P:THR96 4.4 35.4 1.0 HG22 P:THR96 4.4 41.0 1.0 HE1 P:TYR97 4.4 47.5 1.0 HB3 M:ASP99 4.5 74.3 1.0 HD2 P:TYR97 4.5 35.8 1.0 HE2 P:TYR97 4.6 38.0 1.0 CA P:THR96 4.6 29.9 1.0 CB P:TYR97 4.7 29.9 1.0 HE2 N:TYR32 4.8 35.8 1.0 O P:HOH306 4.8 27.5 1.0 OH P:TYR97 4.8 35.8 1.0 HG21 P:THR96 5.0 41.0 1.0

P.Dosenovic, A.K.Pettersson, A.Wall, E.S.Thientosapol, J.Feng, C.Weidle, K.Bhullar, E.E.Kara, H.Hartweger, J.A.Pai, M.D.Gray, K.R.Parks, J.J.Taylor, M.Pancera, L.Stamatatos, M.C.Nussenzweig, A.T.Mcguire. Anti-Idiotypic Antibodies Elicit Anti-Hiv-1-Specific B Cell Responses. J.Exp.Med. V. 216 2316 2019.
ISSN: ESSN 1540-9538
PubMed: 31345931
DOI: 10.1084/JEM.20190446