Chlorine in PDB 6ooz: Asymmetric Htnf-Alpha

The structure of Asymmetric Htnf-Alpha, PDB code: 6ooz was solved by T.L.Arakaki, T.E.Edwards, D.Fox Iii, F.Lecomte, T.Ceska, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.83 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.520, 81.170, 93.350, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 27.3

The binding sites of Chlorine atom in the Asymmetric Htnf-Alpha (pdb code 6ooz). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Asymmetric Htnf-Alpha, PDB code: 6ooz:

Chlorine binding site 1 out of 1 in the Asymmetric Htnf-Alpha


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Asymmetric Htnf-Alpha within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl201 b:46.9 occ:1.00 N C:ASN92 3.4 33.3 1.0 CB C:ASN92 3.6 29.2 1.0 CG C:ASN92 3.8 28.3 1.0 CB B:SER147 3.8 27.6 1.0 OD1 C:ASN92 4.0 30.5 1.0 OG B:SER147 4.0 27.5 1.0 CA C:ASN92 4.1 30.9 1.0 CA C:VAL91 4.3 39.9 1.0 C C:VAL91 4.3 36.5 1.0 N B:SER147 4.4 26.9 1.0 ND2 C:ASN92 4.4 27.3 1.0 CG1 C:VAL91 4.4 42.1 1.0 CA B:SER147 4.7 27.2 1.0 O C:ASN92 4.8 31.5 1.0 CB C:VAL91 4.8 41.1 1.0 C C:ASN92 5.0 30.0 1.0

J.O'connell, J.Porter, B.Kroeplien, T.Norman, S.Rapecki, R.Davis, D.Mcmillan, T.Arakaki, A.Burgin, D.Fox Iii, T.Ceska, F.Lecomte, A.Maloney, A.Vugler, B.Carrington, B.P.Cossins, T.Bourne, A.Lawson. Small Molecules That Inhibit Tnf Signalling By Stabilising An Asymmetric Form of the Trimer. Nat Commun V. 10 5795 2019.
ISSN: ESSN 2041-1723
PubMed: 31857588
DOI: 10.1038/S41467-019-13616-1