Chlorine in PDB 6ort: Crystal Structure of Bos Taurus MXRA8 Ectodomain

The structure of Crystal Structure of Bos Taurus MXRA8 Ectodomain, PDB code: 6ort was solved by D.H.Fremont, A.S.Kim, C.A.Nelson, Center For Structural Genomics Ofinfectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.98 / 2.30
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	77.530, 77.530, 242.350, 90.00, 90.00, 120.00
R / Rfree (%)	21.8 / 24.2

The binding sites of Chlorine atom in the Crystal Structure of Bos Taurus MXRA8 Ectodomain (pdb code 6ort). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Bos Taurus MXRA8 Ectodomain, PDB code: 6ort:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Bos Taurus MXRA8 Ectodomain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Bos Taurus MXRA8 Ectodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:64.6 occ:1.00 NH1 A:ARG99 2.8 49.4 0.5 CD A:ARG99 3.9 49.6 0.5 O A:GLY101 3.9 75.5 0.5 CZ A:ARG99 4.0 52.1 0.5 NE A:ARG99 4.4 54.9 0.5

Chlorine binding site 2 out of 3 in the Crystal Structure of Bos Taurus MXRA8 Ectodomain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Bos Taurus MXRA8 Ectodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:57.1 occ:1.00 N A:GLU145 3.2 64.0 1.0 NH1 A:ARG194 3.2 82.9 1.0 CD A:ARG194 3.7 71.4 1.0 CB A:GLU145 3.8 74.6 1.0 CA A:GLU144 3.9 53.8 1.0 CG A:ARG194 3.9 56.1 1.0 C A:GLU144 4.0 58.3 1.0 CA A:GLU145 4.0 67.9 1.0 CB A:GLU144 4.1 58.8 1.0 CZ A:ARG194 4.3 80.9 1.0 NE A:ARG194 4.5 75.8 1.0 CG A:GLU144 4.7 73.4 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Bos Taurus MXRA8 Ectodomain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Bos Taurus MXRA8 Ectodomain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:56.6 occ:1.00 N A:ALA265 3.0 43.2 1.0 O A:HOH553 3.2 39.0 1.0 O A:HOH527 3.3 61.6 1.0 NH2 A:ARG247 3.4 46.9 1.0 CA A:ASP264 3.6 59.7 1.0 N A:ASP264 3.7 53.2 1.0 C A:ASP264 3.7 49.6 1.0 N A:PHE266 3.8 35.8 1.0 CB A:ALA265 3.9 37.0 1.0 CA A:ALA265 3.9 41.8 1.0 CD2 A:PHE266 4.1 37.3 1.0 NE A:ARG247 4.2 51.2 1.0 CZ A:ARG247 4.3 46.6 1.0 C A:ALA265 4.4 40.4 1.0 CA A:GLY245 4.4 43.2 1.0 C A:ALA263 4.7 51.1 1.0 CB A:PHE266 4.7 37.7 1.0 O A:TYR242 4.8 38.4 1.0 CA A:PHE266 4.8 45.2 1.0 O A:ASP264 4.9 45.2 1.0 CG A:PHE266 4.9 40.8 1.0 CE2 A:PHE266 4.9 33.8 1.0 N A:GLY245 4.9 42.7 1.0

A.S.Kim, O.Zimmerman, J.M.Fox, C.A.Nelson, K.Basore, R.Zhang, L.Durnell, C.Desai, C.Bullock, S.L.Deem, J.Oppenheimer, B.Shapiro, T.Wang, S.Cherry, C.B.Coyne, S.A.Handley, M.J.Landis, D.H.Fremont, M.S.Diamond. An Evolutionary Insertion in the MXRA8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe 2020.
ISSN: ESSN 1934-6069
PubMed: 32075743
DOI: 10.1016/J.CHOM.2020.01.008