Chlorine in PDB 6os0: Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II

Protein crystallography data

The structure of Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II, PDB code: 6os0 was solved by L.M.Wingler, D.P.Staus, M.A.Skiba, C.Mcmahon, A.L.W.Kleinhenz, R.J.Lefkowitz, A.C.Kruse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.20 / 2.90
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 135.530, 37.830, 111.920, 90.00, 94.41, 90.00
R / Rfree (%) 25.9 / 31.8

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II (pdb code 6os0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II, PDB code: 6os0:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6os0

Go back to Chlorine Binding Sites List in 6os0
Chlorine binding site 1 out of 2 in the Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2002

b:73.3
occ:1.00
CA A:HIS132 3.4 75.1 1.0
CG A:LYS135 3.5 67.4 1.0
CB A:HIS132 3.5 85.5 1.0
N A:LYS135 3.6 67.9 1.0
C A:HIS132 3.7 59.5 1.0
CB A:LYS135 3.8 82.2 1.0
CD A:LYS135 3.9 78.0 1.0
N A:MET134 4.0 67.2 1.0
N A:PRO133 4.1 56.9 1.0
CB A:MET134 4.2 62.7 1.0
ND1 A:HIS132 4.3 82.9 1.0
O A:HIS132 4.3 51.1 1.0
CA A:LYS135 4.4 72.8 1.0
CD A:PRO133 4.4 61.8 1.0
CG A:HIS132 4.4 77.7 1.0
CE A:LYS135 4.4 75.4 1.0
CA A:MET134 4.4 54.0 1.0
C A:MET134 4.5 60.5 1.0
O A:VAL131 4.5 70.7 1.0
N A:HIS132 4.7 64.4 1.0
CG A:MET134 4.7 70.7 1.0
C A:PRO133 4.9 61.0 1.0

Chlorine binding site 2 out of 2 in 6os0

Go back to Chlorine Binding Sites List in 6os0
Chlorine binding site 2 out of 2 in the Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Synthetic Nanobody-Stabilized Angiotensin II Type 1 Receptor Bound to Angiotensin II within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2003

b:78.5
occ:1.00
N D:TYR109 3.3 64.9 1.0
CB A:LYS1308 3.4 91.6 1.0
N A:LYS1308 3.4 77.2 1.0
N A:PHE1309 3.6 92.0 1.0
OD1 D:ASP108 3.6 73.7 1.0
CA A:GLY1306 3.6 66.1 1.0
N D:ASP110 3.7 74.7 1.0
CA A:LYS1308 3.8 77.3 1.0
C A:GLY1306 3.8 66.0 1.0
CA D:ASP108 4.0 47.1 1.0
N A:LYS1307 4.0 56.8 1.0
CD2 D:TYR109 4.0 56.5 1.0
CA D:TYR109 4.1 60.2 1.0
C D:ASP108 4.1 63.8 1.0
C A:LYS1308 4.1 94.3 1.0
CB D:ASP110 4.2 84.9 1.0
CB D:TYR109 4.2 49.6 1.0
C D:TYR109 4.3 70.3 1.0
CG D:ASP108 4.3 72.6 1.0
O A:GLY1306 4.4 67.2 1.0
CB A:PHE1309 4.4 75.6 1.0
C A:LYS1307 4.5 86.2 1.0
CG D:TYR109 4.6 57.9 1.0
CA A:PHE1309 4.6 74.3 1.0
SD A:MET57 4.6 98.8 1.0
CA D:ASP110 4.6 71.2 1.0
CB D:ASP108 4.8 61.8 1.0
O D:PHE107 4.8 53.0 1.0
CA A:LYS1307 4.9 81.6 1.0
N A:GLY1306 5.0 65.7 1.0
N D:ASP108 5.0 53.3 1.0
CE2 D:TYR109 5.0 52.6 1.0

Reference:

L.M.Wingler, M.A.Skiba, C.Mcmahon, D.P.Staus, A.L.W.Kleinhenz, C.-M.Suomivuori, N.R.Latorraca, R.O.Dror, R.J.Lefkowitz, A.C.Kruse. Angiotensin and Biased Analogs Induce Structurally Distinct Active Conformations Within A Gpcr Science 2020.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.AAY9813
Page generated: Sat Dec 12 13:27:41 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy