Chlorine in PDB 6otc: Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain

The structure of Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain, PDB code: 6otc was solved by P.Amatya, G.Chen, D.Borek, S.S.Sidhu, D.W.Leung, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.96 / 1.70
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.827, 97.422, 110.325, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 23.3

The binding sites of Chlorine atom in the Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain (pdb code 6otc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain, PDB code: 6otc:

Chlorine binding site 1 out of 1 in the Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Synthetic Fab Bound to Marburg Virus VP35 Interferon Inhibitory Domain within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl302 b:17.4 occ:1.00 O H:HOH618 3.0 13.7 1.0 N H:TRP105 3.1 15.2 1.0 N H:TYR106 3.2 15.8 0.5 N H:TYR106 3.2 15.4 0.5 CB H:ALA108 3.4 13.2 1.0 N H:ALA108 3.4 12.3 1.0 CB H:TRP105 3.7 18.6 1.0 CA H:TRP105 3.8 16.6 1.0 CA H:ALA108 3.8 12.3 1.0 OG H:SER104 3.8 11.8 1.0 CD2 H:TYR106 3.9 20.3 0.5 N H:GLY107 3.9 14.0 1.0 O H:ALA108 3.9 11.6 1.0 CB L:SER50 4.0 15.1 1.0 C H:TRP105 4.0 16.5 1.0 CE3 H:TRP105 4.1 20.6 1.0 CA H:TYR106 4.1 16.1 0.5 C H:ALA108 4.1 11.4 1.0 C H:TYR106 4.2 14.8 0.5 C H:SER104 4.2 13.5 1.0 CA H:TYR106 4.2 15.4 0.5 C H:TYR106 4.2 15.1 0.5 CA H:SER104 4.3 12.3 1.0 CB H:TYR106 4.3 17.8 0.5 OG L:SER50 4.4 16.7 1.0 CG H:TYR106 4.4 19.1 0.5 CD2 L:TYR49 4.5 14.4 1.0 C H:GLY107 4.5 12.7 1.0 CE2 H:TYR106 4.6 21.3 0.5 CG H:TRP105 4.6 19.8 1.0 CB H:SER104 4.7 11.8 1.0 CD2 H:TRP105 4.7 20.8 1.0 O L:HOH443 4.7 13.0 1.0 CB H:TYR106 4.8 16.4 0.5 CA L:SER50 4.8 14.9 1.0 CA H:GLY107 4.8 13.3 1.0 N L:SER50 4.9 14.1 1.0 O H:TYR106 4.9 15.3 0.5

P.Amatya, N.Wagner, G.Chen, P.Luthra, L.Shi, D.Borek, A.Pavlenco, H.Rohrs, C.F.Basler, S.S.Sidhu, M.L.Gross, D.W.Leung. Inhibition of Marburg Virus Rna Synthesis By A Synthetic Anti-VP35 Antibody. Acs Infect Dis. V. 5 1385 2019.
ISSN: ESSN 2373-8227
PubMed: 31120240
DOI: 10.1021/ACSINFECDIS.9B00091