Chlorine in PDB 6p5z: Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase

All present enzymatic activity of Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase:
1.3.1.76; 2.1.1.107; 4.99.1.4;

The structure of Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase, PDB code: 6p5z was solved by J.M.Pennington, M.E.Stroupe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.34 / 2.26
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.601, 100.446, 146.4, 90, 90, 90
R / Rfree (%)	17.9 / 24.2

The structure of Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase also contains other interesting chemical elements:

Cobalt

(Co)

2 atoms

The binding sites of Chlorine atom in the Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase (pdb code 6p5z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase, PDB code: 6p5z:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl504 b:106.0 occ:1.00 N A:ARG309 3.1 51.9 1.0 OG1 B:THR345 3.4 50.5 1.0 CA A:ARG309 3.4 54.5 1.0 CG A:ARG309 3.7 77.8 1.0 N A:GLY308 3.9 71.0 1.0 CA A:PHE307 3.9 63.4 1.0 N B:HIS346 4.0 54.1 1.0 C A:PHE307 4.0 70.9 1.0 CA B:HIS346 4.0 55.9 1.0 CB A:ARG309 4.1 60.6 1.0 N B:ARG347 4.1 61.9 1.0 CB B:THR345 4.2 51.6 1.0 C B:THR345 4.2 54.3 1.0 C A:GLY308 4.3 63.8 1.0 NH1 A:ARG309 4.4 131.1 1.0 O B:THR345 4.4 56.4 1.0 N A:PHE307 4.4 47.3 1.0 C B:HIS346 4.5 67.1 1.0 CD A:ARG309 4.5 97.5 1.0 CA A:GLY308 4.7 69.4 1.0 C A:ARG309 4.7 56.3 1.0 O A:PHE307 4.8 70.8 1.0 CA B:THR345 4.9 53.2 1.0

Chlorine binding site 2 out of 2 in the Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cobalt-Sirohydrochlorin-Bound S. Typhimurium Siroheme Synthase within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl502 b:64.4 occ:1.00 N B:GLY130 3.0 77.6 1.0 N B:SER132 3.3 57.8 1.0 N B:ALA128 3.3 57.3 1.0 C B:SER132 3.3 70.6 1.0 CA B:GLY130 3.4 74.2 1.0 O B:SER132 3.5 73.4 1.0 N B:PRO133 3.5 64.5 1.0 C B:ALA128 3.6 65.7 1.0 N B:THR131 3.7 70.5 1.0 C B:GLY130 3.7 83.8 1.0 CA B:ALA128 3.7 62.9 1.0 CB B:ALA128 3.7 49.4 1.0 N B:GLY129 3.8 62.9 1.0 CA B:SER132 3.8 70.5 1.0 CA B:PRO133 4.0 55.5 1.0 CD B:PRO133 4.0 60.0 1.0 O B:ALA128 4.1 65.5 1.0 C B:GLY129 4.1 80.4 1.0 OG B:SER127 4.3 62.3 1.0 C B:THR131 4.4 68.5 1.0 CB B:SER132 4.5 77.0 1.0 C B:SER127 4.5 54.8 1.0 CA B:GLY129 4.5 70.9 1.0 O B:GLY130 4.6 94.5 1.0 CA B:THR131 4.6 79.7 1.0 CA B:SER127 4.7 50.2 1.0 CB B:ALA136 4.8 45.7 1.0 CB B:PRO133 4.8 63.2 1.0 OG1 B:THR131 5.0 66.5 1.0

J.M.Pennington, M.E.Stroupe. Siroheme Synthase Orients Substrates For Dehydrogenase and Chelatase Activities in A Single Active Site To Be Published.