Chlorine in PDB 6p8c: 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus

Enzymatic activity of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus

All present enzymatic activity of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus:
1.1.1.302;

Protein crystallography data

The structure of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus, PDB code: 6p8c was solved by V.Carbone, L.R.Schofield, I.Hannus, A.J.Sutherland-Smith, R.S.Ronimus, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 45.98 / 2.07
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 56.921, 89.597, 107.013, 90.00, 90.00, 90.00
R / Rfree (%) 17.1 / 22.2

Other elements in 6p8c:

The structure of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus (pdb code 6p8c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus, PDB code: 6p8c:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 6p8c

Go back to Chlorine Binding Sites List in 6p8c
Chlorine binding site 1 out of 2 in the 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl301

b:50.4
occ:1.00
 O A:HOH489 3.0 50.1 1.0
N A:LEU59 3.1 30.3 1.0
NH1 A:ARG39 3.4 27.8 1.0
NE2 A:HIS62 3.5 38.4 1.0
O A:HOH445 3.5 50.5 1.0
N A:ARG58 3.7 31.2 1.0
CA A:LEU59 3.8 34.0 1.0
NH2 A:ARG39 3.9 28.3 1.0
CZ A:ARG39 4.1 32.0 1.0
C A:ARG58 4.1 29.9 1.0
CB A:PRO57 4.1 30.2 1.0
CA A:ARG58 4.2 31.5 1.0
CB A:ARG58 4.2 32.0 1.0
N A:THR60 4.2 30.8 1.0
CE1 A:HIS62 4.3 35.8 1.0
CD2 A:HIS62 4.4 36.9 1.0
C A:PRO57 4.5 32.6 1.0
O A:HOH522 4.5 41.9 0.5
C A:LEU59 4.5 31.2 1.0
CA A:PRO57 4.5 31.5 1.0
CD2 A:LEU59 4.6 30.6 1.0
O A:THR60 4.7 29.0 1.0
CE1 A:HIS36 4.8 31.7 1.0
NE2 A:HIS36 4.8 32.8 1.0
CB A:LEU59 5.0 30.2 1.0

Chlorine binding site 2 out of 2 in 6p8c

Go back to Chlorine Binding Sites List in 6p8c
Chlorine binding site 2 out of 2 in the 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl301

b:57.1
occ:1.00
 O B:HOH474 2.9 43.8 1.0
N B:LEU59 3.1 34.2 1.0
NH1 B:ARG39 3.2 30.9 1.0
O B:HOH464 3.5 67.8 1.0
N B:ARG58 3.6 34.7 1.0
CA B:LEU59 3.7 33.8 1.0
NE2 B:HIS62 3.8 41.5 1.0
NH2 B:ARG39 3.8 28.1 1.0
CZ B:ARG39 4.0 33.7 1.0
C B:ARG58 4.1 32.1 1.0
CB B:ARG58 4.2 34.8 1.0
CA B:ARG58 4.2 34.5 1.0
CB B:PRO57 4.2 29.9 1.0
N B:THR60 4.3 34.4 1.0
C B:PRO57 4.5 35.9 1.0
C B:LEU59 4.6 37.3 1.0
CD2 B:LEU59 4.6 36.0 1.0
CA B:PRO57 4.6 36.6 1.0
CD2 B:HIS62 4.6 40.1 1.0
CE1 B:HIS62 4.7 41.4 1.0
NE2 B:HIS36 4.7 33.7 1.0
O B:THR60 4.7 31.8 1.0
CB B:LEU59 4.9 34.0 1.0
CE1 B:HIS36 4.9 38.5 1.0

Reference:

V.Carbone, L.R.Schofield, I.Hannus, A.J.Sutherland-Smith, R.S.Ronimus. The Crystal Structure of 2,5-Diamino-6-(Ribosylamino)-4(3H)-Pyrimidinone 5'-Phosphate Reductase (Mthred) From Methanothermobacter Thermautotrophicus To Be Published.
Page generated: Sat Dec 12 13:29:11 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy