Chlorine in PDB 6pa7: The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome.

All present enzymatic activity of The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome.:
2.1.1.37;

The binding sites of Chlorine atom in the The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome. (pdb code 6pa7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome., PDB code: 6pa7:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:50.8 occ:0.71 CG A:LYS122 3.6 42.0 1.0 CD A:PRO121 3.6 39.0 1.0 N A:LYS122 3.7 42.0 1.0 CB A:PRO121 4.0 39.0 1.0 CG A:PRO121 4.0 39.0 1.0 N A:PRO121 4.0 39.0 1.0 CE A:LYS122 4.2 42.0 1.0 CD A:LYS122 4.3 42.0 1.0 CB A:LYS122 4.4 42.0 1.0 CA A:PRO121 4.4 39.0 1.0 C A:PRO121 4.4 39.0 1.0 CB A:MET120 4.5 42.8 1.0 CA A:LYS122 4.6 42.0 1.0 CD1 B:LEU49 4.8 40.0 1.0 C A:MET120 4.9 42.8 1.0

Chlorine binding site 2 out of 3 in the The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome. within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl201 b:56.2 occ:1.00 N C:GLY46 3.3 50.1 1.0 OP1 I:DT122 3.6 56.9 1.0 CA C:GLY46 3.6 50.1 1.0 CB D:THR87 3.6 43.9 1.0 N D:SER88 3.6 43.9 1.0 CA D:THR87 3.7 43.9 1.0 N C:ALA47 3.9 48.7 1.0 CG2 D:THR87 4.0 43.9 1.0 N C:ALA45 4.1 52.5 1.0 C D:THR87 4.1 43.9 1.0 C C:GLY46 4.1 50.1 1.0 CA C:GLY44 4.3 54.9 1.0 C C:ALA45 4.5 52.5 1.0 CB D:SER88 4.6 43.9 1.0 OG D:SER88 4.6 43.9 1.0 C C:GLY44 4.7 54.9 1.0 CA D:SER88 4.7 43.9 1.0 P I:DT122 4.8 56.9 1.0 CA C:ALA45 4.9 52.5 1.0 OG1 D:THR87 4.9 43.9 1.0 N D:THR87 5.0 43.9 1.0 O D:ILE86 5.0 47.2 1.0

Chlorine binding site 3 out of 3 in the The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Cryo-Em Structure of the Human DNMT3A2-DNMT3B3 Complex Bound to Nucleosome. within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl201 b:59.5 occ:1.00 N H:SER88 3.4 42.4 1.0 CA G:GLY46 3.5 46.0 1.0 CB H:THR87 3.6 41.7 1.0 N G:GLY46 3.6 46.0 1.0 OG H:SER88 3.8 42.4 1.0 CB H:SER88 4.0 42.4 1.0 CA H:THR87 4.0 41.7 1.0 CG2 H:THR87 4.1 41.7 1.0 C G:GLY46 4.2 46.0 1.0 C H:THR87 4.2 41.7 1.0 N G:ALA47 4.2 43.1 1.0 OP1 J:DG122 4.2 43.6 1.0 CA H:SER88 4.3 42.4 1.0 OG1 H:THR87 4.7 41.7 1.0 N G:ALA45 4.9 46.7 1.0 C G:ALA45 4.9 46.7 1.0

T.H.Xu, M.Liu, X.E.Zhou, G.Liang, G.Zhao, H.E.Xu, K.Melcher, P.A.Jones. He Nucleosomal Acidic Patch and Linker Dna Help Anchor the De Novo Dna Methyltransferase DNMT3A2/3B3 Complex To Be Published.