Chlorine in PDB 6psg: Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem

All present enzymatic activity of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem:
3.5.2.6;

The structure of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem, PDB code: 6psg was solved by A.Akhtar, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.12 / 2.13
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	59.555, 106.674, 96.261, 90.00, 104.19, 90.00
R / Rfree (%)	17.1 / 22

The binding sites of Chlorine atom in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem (pdb code 6psg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem, PDB code: 6psg:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:29.5 occ:1.00 NH1 B:ARG206 3.1 20.4 1.0 NH1 A:ARG206 3.1 25.0 1.0 NH2 A:ARG206 3.2 24.7 1.0 NH2 B:ARG206 3.2 26.4 1.0 CZ B:ARG206 3.6 25.6 1.0 CZ A:ARG206 3.6 33.5 1.0 CG B:GLN193 4.3 28.9 1.0 CA A:GLN193 4.4 26.6 1.0 CG A:GLN193 4.4 32.6 1.0 CD2 A:LEU196 4.4 20.2 1.0 CA B:GLN193 4.4 28.1 1.0 CD2 B:LEU196 4.4 27.8 1.0 CB B:GLN193 4.6 26.3 1.0 CB A:GLN193 4.7 24.7 1.0 CB B:LEU196 4.8 28.8 1.0 CB A:LEU196 4.8 27.5 1.0 O A:GLN193 4.9 24.4 1.0 NE B:ARG206 4.9 25.1 1.0 NE A:ARG206 4.9 24.7 1.0 O B:GLN193 4.9 25.1 1.0 CG A:LEU196 5.0 27.9 1.0 CG B:LEU196 5.0 29.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl301 b:29.5 occ:1.00 NH1 D:ARG206 3.1 24.2 1.0 NH2 D:ARG206 3.1 25.3 1.0 NH1 C:ARG206 3.1 23.1 1.0 NH2 C:ARG206 3.3 25.3 1.0 CZ D:ARG206 3.5 27.6 1.0 CZ C:ARG206 3.6 31.0 1.0 CD2 D:LEU196 4.2 22.5 1.0 CG D:GLN193 4.2 27.2 1.0 CA C:GLN193 4.3 28.8 1.0 CD2 C:LEU196 4.3 25.1 1.0 CA D:GLN193 4.3 24.4 1.0 CG C:GLN193 4.4 31.6 1.0 CB D:GLN193 4.5 28.0 1.0 CB C:GLN193 4.5 24.1 1.0 CB C:LEU196 4.9 22.5 1.0 NE D:ARG206 4.9 25.6 1.0 O C:GLN193 4.9 25.1 1.0 CB D:LEU196 4.9 27.0 1.0 CG C:LEU196 4.9 28.4 1.0 O D:GLN193 4.9 21.9 1.0 NE C:ARG206 4.9 25.0 1.0 CD1 C:LEU196 5.0 26.1 1.0 CG D:LEU196 5.0 27.4 1.0 O D:HOH428 5.0 37.1 1.0

A.Akhtar, Y.Chen. Crystal Structure of Class D Beta-Lactamase Oxa-48 with Faropenem To Be Published.