Chlorine in PDB 6pt5: Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin

All present enzymatic activity of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin:
3.5.2.6;

The structure of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin, PDB code: 6pt5 was solved by A.Akhtar, Y.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.10 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.246, 107.115, 96.105, 90.00, 104.06, 90.00
R / Rfree (%)	19.3 / 24.2

The binding sites of Chlorine atom in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin (pdb code 6pt5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin, PDB code: 6pt5:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:37.5 occ:1.00 NH1 A:ARG206 3.1 37.4 1.0 NH2 C:ARG206 3.1 32.7 1.0 NH2 A:ARG206 3.1 39.1 1.0 NH1 C:ARG206 3.1 35.5 1.0 CZ A:ARG206 3.5 38.1 1.0 CZ C:ARG206 3.6 36.0 1.0 CD2 C:LEU196 4.2 33.4 1.0 CD2 A:LEU196 4.2 32.5 1.0 CA A:GLN193 4.4 37.6 1.0 CA C:GLN193 4.4 34.1 1.0 CG C:GLN193 4.4 40.0 1.0 CB C:GLN193 4.6 35.0 1.0 CG A:GLN193 4.6 40.1 1.0 CB A:GLN193 4.6 36.5 1.0 CB A:LEU196 4.8 36.5 1.0 NE A:ARG206 4.8 39.2 1.0 O A:GLN193 4.9 43.1 1.0 CG A:LEU196 4.9 37.2 1.0 CB C:LEU196 4.9 39.8 1.0 NE C:ARG206 4.9 45.7 1.0 CG C:LEU196 4.9 39.0 1.0 O C:GLN193 4.9 40.6 1.0 CD1 A:LEU196 5.0 39.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl301 b:38.5 occ:1.00 NH1 D:ARG206 3.0 36.8 1.0 NH2 B:ARG206 3.1 43.0 1.0 NH1 B:ARG206 3.2 36.8 1.0 NH2 D:ARG206 3.3 35.0 1.0 CZ B:ARG206 3.6 44.6 1.0 CZ D:ARG206 3.6 36.1 1.0 CD2 B:LEU196 4.0 29.7 1.0 CD2 D:LEU196 4.2 35.8 1.0 CA D:GLN193 4.3 42.6 1.0 CG D:GLN193 4.4 43.9 1.0 CA B:GLN193 4.4 34.6 1.0 CB D:GLN193 4.5 41.0 1.0 CG B:GLN193 4.6 40.4 1.0 CB B:GLN193 4.7 38.2 1.0 CB D:LEU196 4.8 38.2 1.0 CB B:LEU196 4.8 37.9 1.0 O D:GLN193 4.8 40.5 1.0 CG B:LEU196 4.9 35.6 1.0 CG D:LEU196 4.9 39.5 1.0 NE D:ARG206 4.9 44.1 1.0 NE B:ARG206 4.9 39.2 1.0 O B:GLN193 4.9 41.3 1.0 CD1 D:LEU196 4.9 35.7 1.0

A.Akhtar, Y.Chen. Crystal Structure of Class D Beta-Lactamase Oxa-48 with Cefoxitin To Be Published.