Chlorine in PDB 6q62: Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)

Enzymatic activity of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)

All present enzymatic activity of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine):
2.5.1.15;

Protein crystallography data

The structure of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine), PDB code: 6q62 was solved by A.A.Oliveira, M.Hyvonen, R.V.C.Guido, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.09 / 1.50
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 82.382, 74.553, 89.299, 90.00, 101.21, 90.00
R / Rfree (%) 21.1 / 23.9

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) (pdb code 6q62). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine), PDB code: 6q62:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 6q62

Go back to Chlorine Binding Sites List in 6q62
Chlorine binding site 1 out of 4 in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl401

b:33.0
occ:1.00
 CL6 A:6GU401 0.0 33.0 1.0
C6 A:6GU401 1.6 21.8 1.0
N1 A:6GU401 2.5 18.6 1.0
C5 A:6GU401 2.5 20.2 1.0
O A:HOH513 2.7 10.4 1.0
NZ A:LYS226 2.8 22.4 1.0
N7 A:6GU401 3.1 20.5 1.0
O A:GLY222 3.2 11.4 1.0
CA A:GLY222 3.6 8.1 1.0
C2 A:6GU401 3.8 16.8 1.0
C4 A:6GU401 3.8 13.5 1.0
C A:GLY222 3.8 11.9 1.0
N A:GLY222 4.0 10.1 1.0
O A:PHE193 4.1 13.0 1.0
OD2 A:ASP190 4.1 15.7 1.0
CE1 A:PHE195 4.1 17.1 1.0
CE A:LYS226 4.1 17.0 1.0
O A:HOH584 4.2 18.3 1.0
N A:PHE193 4.3 10.8 1.0
OD1 A:ASP190 4.3 12.3 1.0
N3 A:6GU401 4.4 12.4 1.0
C8 A:6GU401 4.4 20.9 1.0
SD A:MET144 4.5 13.5 1.0
CA A:GLY192 4.6 8.2 1.0
CG A:ASP190 4.6 13.5 1.0
CD1 A:PHE195 4.6 17.4 1.0
C A:GLY192 4.7 13.7 1.0
N2 A:6GU401 4.8 20.1 1.0
N9 A:6GU401 4.8 18.1 1.0
C A:PHE193 4.9 13.1 1.0
CA A:PHE193 5.0 9.8 1.0

Chlorine binding site 2 out of 4 in 6q62

Go back to Chlorine Binding Sites List in 6q62
Chlorine binding site 2 out of 4 in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl401

b:39.0
occ:1.00
 CL6 C:6GU401 0.0 39.0 1.0
C6 C:6GU401 1.6 29.1 1.0
N1 C:6GU401 2.5 24.1 1.0
C5 C:6GU401 2.5 25.9 1.0
O C:HOH507 2.7 17.6 1.0
NZ C:LYS226 2.8 23.2 1.0
N7 C:6GU401 3.1 26.1 1.0
O C:GLY222 3.2 19.0 1.0
CA C:GLY222 3.7 14.9 1.0
C2 C:6GU401 3.8 23.9 1.0
C4 C:6GU401 3.8 23.1 1.0
C C:GLY222 3.9 18.6 1.0
CE1 C:PHE195 4.0 36.2 1.0
O C:PHE193 4.0 19.4 1.0
OD2 C:ASP190 4.1 24.8 1.0
N C:GLY222 4.1 15.6 1.0
CE C:LYS226 4.2 25.9 1.0
N C:PHE193 4.2 18.8 1.0
O C:HOH566 4.3 24.8 1.0
OD1 C:ASP190 4.3 20.7 1.0
N3 C:6GU401 4.4 22.9 1.0
SD C:MET144 4.4 22.8 1.0
C8 C:6GU401 4.5 25.1 1.0
CA C:GLY192 4.6 18.7 1.0
CD1 C:PHE195 4.6 35.6 1.0
CG C:ASP190 4.6 23.0 1.0
C C:GLY192 4.7 22.8 1.0
N2 C:6GU401 4.7 22.1 1.0
N9 C:6GU401 4.8 24.5 1.0
C C:PHE193 4.9 21.0 1.0
CA C:PHE193 5.0 17.6 1.0

Chlorine binding site 3 out of 4 in 6q62

Go back to Chlorine Binding Sites List in 6q62
Chlorine binding site 3 out of 4 in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl401

b:34.6
occ:1.00
 CL6 B:6GU401 0.0 34.6 1.0
C6 B:6GU401 1.6 23.3 1.0
N1 B:6GU401 2.5 16.9 1.0
C5 B:6GU401 2.6 18.9 1.0
O B:HOH516 2.7 11.6 1.0
NZ B:LYS226 2.8 25.7 1.0
N7 B:6GU401 3.1 20.5 1.0
O B:GLY222 3.2 10.2 1.0
CA B:GLY222 3.7 5.3 1.0
C2 B:6GU401 3.8 15.0 1.0
C B:GLY222 3.8 10.2 1.0
C4 B:6GU401 3.8 16.9 1.0
CE1 B:PHE195 4.0 19.4 1.0
O B:PHE193 4.0 12.9 1.0
OD2 B:ASP190 4.0 14.6 1.0
N B:GLY222 4.1 7.4 1.0
CE B:LYS226 4.1 20.1 1.0
O B:HOH595 4.2 19.6 1.0
N B:PHE193 4.3 8.2 1.0
OD1 B:ASP190 4.3 11.4 1.0
N3 B:6GU401 4.4 13.5 1.0
SD B:MET144 4.4 12.3 1.0
C8 B:6GU401 4.5 18.2 1.0
CD1 B:PHE195 4.6 18.5 1.0
CG B:ASP190 4.6 14.6 1.0
CA B:GLY192 4.6 9.8 1.0
N2 B:6GU401 4.7 15.5 1.0
C B:GLY192 4.7 12.9 1.0
N9 B:6GU401 4.8 20.4 1.0
C B:PHE193 4.9 14.0 1.0

Chlorine binding site 4 out of 4 in 6q62

Go back to Chlorine Binding Sites List in 6q62
Chlorine binding site 4 out of 4 in the Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl401

b:37.0
occ:1.00
 CL6 D:6GU401 0.0 37.0 1.0
C6 D:6GU401 1.6 27.5 1.0
N1 D:6GU401 2.5 18.7 1.0
C5 D:6GU401 2.6 22.5 1.0
O D:HOH506 2.7 12.6 1.0
NZ D:LYS226 2.8 23.8 1.0
N7 D:6GU401 3.2 23.5 1.0
O D:GLY222 3.2 11.8 1.0
CA D:GLY222 3.6 8.4 1.0
C2 D:6GU401 3.8 17.6 1.0
C D:GLY222 3.8 10.9 1.0
C4 D:6GU401 3.8 19.8 1.0
N D:GLY222 4.0 9.5 1.0
O D:PHE193 4.0 14.4 1.0
CE1 D:PHE195 4.0 22.4 1.0
OD2 D:ASP190 4.0 19.1 1.0
CE D:LYS226 4.1 18.8 1.0
O D:HOH578 4.3 17.1 1.0
N D:PHE193 4.3 11.1 1.0
OD1 D:ASP190 4.3 15.6 1.0
N3 D:6GU401 4.4 18.7 1.0
SD D:MET144 4.4 14.7 1.0
C8 D:6GU401 4.5 21.6 1.0
CA D:GLY192 4.6 11.0 1.0
CD1 D:PHE195 4.6 21.9 1.0
CG D:ASP190 4.6 16.3 1.0
C D:GLY192 4.7 14.3 1.0
N2 D:6GU401 4.7 15.8 1.0
N9 D:6GU401 4.8 23.0 1.0
C D:PHE193 4.9 16.3 1.0
CA D:PHE193 5.0 10.8 1.0

Reference:

A.A.Oliveira, M.Hyvonen, R.V.C.Guido. Xanthomonas Albilineans Dihydropteroate Synthase in Complex with (Indole-2-Carboxylic Acid) and (6-Chloroguanine) To Be Published.
Page generated: Sat Dec 12 13:32:45 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy