Chlorine in PDB 6qau: Crystal Structure of ULK2 in Complexed with MRT67307

Enzymatic activity of Crystal Structure of ULK2 in Complexed with MRT67307

All present enzymatic activity of Crystal Structure of ULK2 in Complexed with MRT67307:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of ULK2 in Complexed with MRT67307, PDB code: 6qau was solved by A.Chaikuad, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp, Structuralgenomics Consortium, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 58.50 / 2.48
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 117.006, 117.006, 141.485, 90.00, 90.00, 120.00
R / Rfree (%) 19.6 / 23.7

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of ULK2 in Complexed with MRT67307 (pdb code 6qau). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of ULK2 in Complexed with MRT67307, PDB code: 6qau:

Chlorine binding site 1 out of 1 in 6qau

Go back to Chlorine Binding Sites List in 6qau
Chlorine binding site 1 out of 1 in the Crystal Structure of ULK2 in Complexed with MRT67307


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of ULK2 in Complexed with MRT67307 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl307

b:62.5
occ:1.00
O A:HOH433 3.5 41.1 1.0
N A:TYR164 3.5 41.3 1.0
CD2 A:TYR164 4.0 47.7 1.0
CB A:TYR164 4.1 45.2 1.0
CA A:ARG163 4.1 37.6 1.0
CB A:ARG163 4.2 36.4 1.0
CA A:TYR164 4.3 43.6 1.0
C A:ARG163 4.3 39.0 1.0
O A:TYR164 4.5 43.6 1.0
CG A:TYR164 4.5 46.2 1.0
CD A:LYS55 4.8 41.0 1.0
C A:TYR164 4.9 44.1 1.0

Reference:

A.Chaikuad, S.E.Koschade, A.Stolz, K.Zivkovic, C.Pohl, S.Shaid, H.Ren, L.J.Lambert, N.D.P.Cosford, C.H.Brandts, S.Knapp. Conservation of Structure, Function and Inhibitor Binding in Unc-51-Like Kinase 1 and 2 (ULK1/2). Biochem.J. V. 476 875 2019.
ISSN: ESSN 1470-8728
PubMed: 30782972
DOI: 10.1042/BCJ20190038
Page generated: Sat Dec 12 13:33:16 2020

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