Chlorine in PDB 6qdu: Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc

The structure of Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc, PDB code: 6qdu was solved by S.A.Andrei, A.Kaplan, A.E.Fournier, C.Ottman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.88 / 1.63
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	82.854, 111.737, 62.802, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 19.6

The structure of Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc (pdb code 6qdu). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc, PDB code: 6qdu:

Chlorine binding site 1 out of 1 in the Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of 14-3-3SIGMA in Complex with A RAPGEF2 PT740 Phosphopeptide Inhibited By Semi-Synthetic Fusicoccane Fc-Ncpc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:15.2 occ:0.95 HZ1 A:LYS9 2.2 16.0 1.0 HD3 A:LYS9 3.0 12.7 1.0 NZ A:LYS9 3.0 13.3 1.0 HZ2 A:LYS9 3.5 16.0 1.0 HZ3 A:LYS9 3.5 16.0 1.0 HE2 A:LYS9 3.5 14.8 1.0 CE A:LYS9 3.6 12.3 1.0 HZ A:PHE25 3.6 13.8 1.0 CD A:LYS9 3.7 10.5 1.0 HE2 A:MET1 4.0 19.5 1.0 HE2 A:PHE25 4.0 12.1 1.0 HD2 A:LYS9 4.1 12.7 1.0 CZ A:PHE25 4.3 11.4 1.0 CE2 A:PHE25 4.5 10.1 1.0 HE3 A:LYS9 4.6 14.8 1.0 HE3 A:MET1 4.6 19.5 1.0 CE A:MET1 4.7 16.2 1.0 HG2 A:LYS9 4.9 11.2 1.0 CG A:LYS9 4.9 9.3 1.0

A.Kaplan, S.A.Andrei, C.Ottmann, A.E.Fournier. A Single-Agent Polypharmacological Approach to Stimulate Axon Regeneration To Be Published.