Chlorine in PDB 6qid: Crystal Structure of Deah-Box Atpase PRP43-S387A

The structure of Crystal Structure of Deah-Box Atpase PRP43-S387A, PDB code: 6qid was solved by F.Hamann, R.Ficner, M.Enders, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.61 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	88.820, 105.450, 119.230, 90.00, 90.00, 90.00
R / Rfree (%)	18.4 / 20.8

The structure of Crystal Structure of Deah-Box Atpase PRP43-S387A also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Magnesium	(Mg)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of Deah-Box Atpase PRP43-S387A (pdb code 6qid). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure of Deah-Box Atpase PRP43-S387A, PDB code: 6qid:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Crystal Structure of Deah-Box Atpase PRP43-S387A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Deah-Box Atpase PRP43-S387A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1314 b:48.5 occ:1.00 OG1 A:THR381 3.0 20.8 1.0 O A:HOH2004 3.2 37.9 1.0 N A:GLY349 3.3 33.7 1.0 O A:HOH1446 3.5 32.7 1.0 O A:HOH1987 3.6 60.3 1.0 CB A:THR381 3.8 21.8 1.0 O A:HOH1782 3.9 47.8 1.0 CG2 A:THR381 3.9 17.2 1.0 CA A:GLY349 4.0 22.4 1.0 CA A:TYR348 4.2 26.0 1.0 CB A:TYR348 4.3 26.5 1.0 C A:TYR348 4.3 27.7 1.0 NH1 A:ARG152 4.3 67.0 1.0 CB A:ILE383 4.6 25.2 1.0 OD1 A:ASN382 5.0 28.0 1.0

Chlorine binding site 2 out of 5 in the Crystal Structure of Deah-Box Atpase PRP43-S387A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Deah-Box Atpase PRP43-S387A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1315 b:57.4 occ:1.00 O A:HOH1932 2.5 44.6 1.0 N A:ARG153 3.1 27.9 1.0 O A:HOH1713 3.5 31.8 1.0 CG A:ARG153 3.5 40.5 1.0 CD A:ARG153 3.5 46.2 1.0 CA A:ARG152 3.6 22.2 1.0 O A:HOH1896 3.8 43.4 1.0 CB A:ARG153 3.9 33.1 1.0 C A:ARG152 3.9 33.4 1.0 O A:HOH2021 3.9 52.2 1.0 CD A:ARG152 3.9 37.6 1.0 CB A:ARG152 4.0 23.8 1.0 CA A:ARG153 4.1 27.6 1.0 O A:PRO151 4.4 31.5 1.0 CG A:ARG152 4.6 27.5 1.0 N A:ARG152 4.8 20.3 1.0 NE A:ARG153 4.9 60.2 1.0

Chlorine binding site 3 out of 5 in the Crystal Structure of Deah-Box Atpase PRP43-S387A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Deah-Box Atpase PRP43-S387A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1316 b:41.1 occ:1.00 OG1 A:THR195 3.0 32.3 1.0 O A:HOH1895 3.2 51.5 1.0 NH1 A:ARG153 3.3 73.9 1.0 N A:ARG180 3.5 37.9 1.0 NH2 A:ARG201 3.5 43.4 1.0 CG A:ARG153 3.6 40.5 1.0 CG2 A:THR195 3.7 24.0 1.0 CB A:ARG180 3.8 45.6 1.0 CB A:THR195 3.9 28.4 1.0 CD A:ARG153 3.9 46.2 1.0 CB A:ILE179 4.1 35.4 1.0 CA A:ILE179 4.2 36.5 1.0 CA A:ARG180 4.2 40.9 1.0 C A:ILE179 4.3 34.3 1.0 CZ A:ARG153 4.4 70.6 1.0 CG2 A:ILE179 4.4 31.0 1.0 NE A:ARG153 4.6 60.2 1.0 CZ A:ARG201 4.6 40.2 1.0 O A:HOH1767 4.8 63.0 1.0 NH1 A:ARG201 4.8 37.2 1.0 CB A:GLN198 4.8 32.5 1.0 CB A:ARG153 5.0 33.1 1.0 N A:GLN198 5.0 33.5 1.0

Chlorine binding site 4 out of 5 in the Crystal Structure of Deah-Box Atpase PRP43-S387A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Deah-Box Atpase PRP43-S387A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1317 b:85.3 occ:1.00 OE2 A:GLU726 4.3 40.6 1.0 OE2 A:GLU540 4.4 65.7 1.0 CG A:GLU726 4.7 29.9 1.0 O A:HOH1646 4.8 49.2 1.0 O A:GLU726 4.8 36.2 1.0 CD A:GLU726 5.0 37.6 1.0

Chlorine binding site 5 out of 5 in the Crystal Structure of Deah-Box Atpase PRP43-S387A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Deah-Box Atpase PRP43-S387A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1318 b:92.0 occ:1.00 CG2 A:ILE334 4.8 51.2 1.0

F.Hamann, M.Enders, R.Ficner. Structural Basis For Rna Translocation By Deah-Box Atpases. Nucleic Acids Res. V. 47 4349 2019.
ISSN: ESSN 1362-4962
PubMed: 30828714
DOI: 10.1093/NAR/GKZ150