Chlorine in PDB 6rm8: Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp

The structure of Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp, PDB code: 6rm8 was solved by F.Hamann, P.Neumann, R.Ficner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.53 / 1.95
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	64.340, 75.460, 154.440, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 21.8

The structure of Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp (pdb code 6rm8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp, PDB code: 6rm8:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1012 b:76.3 occ:1.00 N A:ARG353 3.2 29.5 1.0 O A:HOH1242 3.4 37.2 1.0 CL A:CL1013 3.6 84.6 1.0 O A:PRO351 3.7 36.7 1.0 CA A:ARG352 3.8 35.5 1.0 CB A:ARG353 3.9 35.4 1.0 O A:HOH1267 3.9 64.2 1.0 C A:ARG352 4.0 31.8 1.0 CA A:ARG353 4.1 32.3 1.0 C A:PRO351 4.6 32.7 1.0 N A:ARG352 4.7 35.3 1.0 CB A:SER547 4.7 41.8 1.0 CB A:ARG352 4.7 36.2 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1013 b:84.6 occ:1.00 NH1 A:ARG352 3.2 40.4 1.0 O A:HOH1133 3.4 39.6 1.0 CD A:ARG352 3.4 45.1 1.0 O A:HOH1242 3.5 37.2 1.0 CL A:CL1012 3.6 76.3 1.0 CB A:SER547 3.8 41.8 1.0 CG1 A:ILE574 3.8 41.5 1.0 CD1 A:ILE574 4.0 36.8 1.0 CZ A:ARG352 4.1 52.1 1.0 NE A:ARG352 4.2 54.1 1.0 CB A:ARG352 4.6 36.2 1.0 CG A:ARG352 4.6 40.2 1.0 CA A:SER547 4.6 34.5 1.0 CA A:ARG352 4.8 35.5 1.0 OG A:SER547 4.9 54.9 1.0 O A:HOH1197 4.9 48.1 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Deah-Box Atpase PRP2 in Complex with SPP2 and Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1014 b:86.1 occ:1.00 N A:ASP673 3.4 43.0 1.0 N A:ASP674 3.6 46.9 1.0 O A:GLY671 3.9 54.9 1.0 CA A:ILE672 4.2 50.4 1.0 CA A:ASP673 4.2 48.8 1.0 CB A:ASP674 4.2 46.9 1.0 CB A:ASP673 4.2 51.0 1.0 C A:ILE672 4.3 49.3 1.0 C A:ASP673 4.4 47.8 1.0 CA A:ASP674 4.5 48.3 1.0 OD2 A:ASP673 4.9 74.8 1.0 C A:GLY671 4.9 49.1 1.0 CG2 A:ILE672 4.9 54.1 1.0 CG A:ASP673 5.0 67.4 1.0

F.Hamann, A.Schmitt, F.Favretto, R.Hofele, P.Neumann, S.Xiang, H.Urlaub, M.Zweckstetter, R.Ficner. Structural Analysis of the Intrinsically Disordered Splicing Factor SPP2 and Its Binding to the Deah-Box Atpase PRP2 Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
DOI: 10.1073/PNAS.1907960117