Chlorine in PDB 6rr0: Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide

All present enzymatic activity of Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide:
3.4.19.12;

The structure of Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide, PDB code: 6rr0 was solved by I.Deshpande, J.J.Keusch, K.Challa, V.Iesmantavicius, S.M.Gasser, H.Gut, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.57 / 2.18
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	70.040, 75.280, 95.910, 90.00, 97.24, 90.00
R / Rfree (%)	19.6 / 21.8

The binding sites of Chlorine atom in the Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide (pdb code 6rr0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide, PDB code: 6rr0:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1101 b:88.0 occ:1.00 CB A:SER1069 3.4 46.8 1.0 N A:MET1071 3.4 46.4 1.0 CD1 A:PHE1070 3.5 47.5 1.0 CG A:MET1071 3.5 62.3 1.0 CE1 A:PHE1070 3.5 49.2 1.0 OE2 A:GLU1039 3.6 86.1 1.0 CB A:MET1071 3.6 55.2 1.0 OG A:SER1069 3.7 56.6 1.0 N A:PHE1070 3.7 43.6 1.0 CA A:GLY1038 4.0 42.4 1.0 C A:GLY1038 4.1 46.3 1.0 SD A:MET1071 4.1 71.7 1.0 CA A:MET1071 4.1 49.4 1.0 CG A:PHE1070 4.1 45.8 1.0 CZ A:PHE1070 4.2 49.7 1.0 C A:SER1069 4.2 45.1 1.0 CA A:SER1069 4.3 40.2 1.0 O A:HOH1215 4.3 70.6 1.0 O A:GLY1038 4.3 45.0 1.0 C A:PHE1070 4.4 47.8 1.0 CA A:PHE1070 4.5 43.1 1.0 N A:GLU1039 4.5 44.6 1.0 CD A:GLU1039 4.5 88.8 1.0 N A:GLY1038 4.6 41.7 1.0 CD2 A:PHE1070 4.7 48.4 1.0 CG A:GLU1039 4.8 63.0 1.0 CE2 A:PHE1070 4.8 52.3 1.0 CB A:PHE1070 4.8 44.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the SIR4 H-Brct Domain in Complex with UBP10 PT123 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1102 b:0.6 occ:1.00 O A:HOH1206 3.5 61.5 1.0 NH1 A:ARG1075 3.5 71.0 1.0 CB A:MET1071 3.6 55.2 1.0 N A:LYS1072 3.9 43.5 1.0 OE2 A:GLU1039 3.9 86.1 1.0 C A:MET1071 4.2 50.2 1.0 OG A:SER1069 4.2 56.6 1.0 NH2 A:ARG1075 4.2 71.7 1.0 CZ A:ARG1075 4.4 88.9 1.0 CA A:LYS1072 4.4 42.7 1.0 CA A:MET1071 4.5 49.4 1.0 CB A:LYS1072 4.6 42.2 1.0 O A:MET1071 4.7 51.7 1.0 CG A:MET1071 4.7 62.3 1.0 CE A:MET1071 4.8 70.8 1.0 SD A:MET1071 4.8 71.7 1.0 CD A:GLU1039 4.9 88.8 1.0

I.Deshpande, J.J.Keusch, K.Challa, V.Iesmantavicius, S.M.Gasser, H.Gut. The SIR4 H-Brct Domain Interacts with Phospho-Proteins to Sequester and Repress Yeast Heterochromatin. Embo J. V. 38 01744 2019.
ISSN: ESSN 1460-2075
PubMed: 31515872
DOI: 10.15252/EMBJ.2019101744