Chlorine in PDB 6sc7: DAB3/Hoip-Rbr-LIGAND3

All present enzymatic activity of DAB3/Hoip-Rbr-LIGAND3:
2.3.2.31;

The structure of DAB3/Hoip-Rbr-LIGAND3, PDB code: 6sc7 was solved by Y.-C.I.Tsai, H.Johansson, D.House, K.Rittinger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	63.39 / 2.56
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	65.712, 86.701, 240.551, 90.00, 90.00, 90.00
R / Rfree (%)	22.4 / 26.7

The structure of DAB3/Hoip-Rbr-LIGAND3 also contains other interesting chemical elements:

Zinc

(Zn)

8 atoms

The binding sites of Chlorine atom in the DAB3/Hoip-Rbr-LIGAND3 (pdb code 6sc7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the DAB3/Hoip-Rbr-LIGAND3, PDB code: 6sc7:

Chlorine binding site 1 out of 1 in the DAB3/Hoip-Rbr-LIGAND3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of DAB3/Hoip-Rbr-LIGAND3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2012 b:57.1 occ:1.00 N B:GLY104 2.8 53.4 1.0 N A:TRP798 3.4 54.6 1.0 CA B:GLY104 3.6 47.2 1.0 CA B:ARG103 3.7 53.4 1.0 C B:ARG103 3.8 56.1 1.0 O A:HOH2102 3.9 58.3 1.0 NZ A:LYS829 3.9 57.1 1.0 CD A:LYS829 3.9 62.3 1.0 CB A:TRP798 3.9 50.0 1.0 CE A:LYS829 3.9 63.1 1.0 CD1 A:TRP798 3.9 52.8 1.0 O A:TRP798 4.1 59.1 1.0 CA A:TRP798 4.1 53.7 1.0 N B:THR105 4.2 47.0 1.0 CA A:LEU797 4.2 54.9 1.0 C A:LEU797 4.2 58.0 1.0 C B:GLY104 4.3 45.9 1.0 O A:PHE796 4.3 61.3 1.0 CG A:TRP798 4.3 52.3 1.0 CB B:ARG103 4.4 57.2 1.0 O B:SER102 4.5 58.5 1.0 C A:TRP798 4.6 55.2 1.0 CG A:LYS829 4.7 59.1 1.0 NZ A:LYS795 4.8 70.6 1.0 N B:ARG103 4.9 57.6 1.0 O B:ARG103 4.9 56.9 1.0 CG A:LEU797 5.0 61.0 1.0 CB A:LEU797 5.0 55.8 1.0

Y.-C.I.Tsai, D.House, K.Rittinger. DAB3/Hoip-Rbr Apo Structure Cell Chem Biol 2019.
ISSN: ESSN 2451-9456