Chlorine in PDB 6sc9: DAB3/Hoip-Rbr-Hoipin-8

All present enzymatic activity of DAB3/Hoip-Rbr-Hoipin-8:
2.3.2.31;

The structure of DAB3/Hoip-Rbr-Hoipin-8, PDB code: 6sc9 was solved by Y.-C.I.Tsai, H.Johansson, D.House, K.Rittinger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	81.90 / 2.47
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	66.127, 87.052, 241.538, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 25.2

The structure of DAB3/Hoip-Rbr-Hoipin-8 also contains other interesting chemical elements:

Fluorine	(F)	2 atoms
Zinc	(Zn)	8 atoms

The binding sites of Chlorine atom in the DAB3/Hoip-Rbr-Hoipin-8 (pdb code 6sc9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the DAB3/Hoip-Rbr-Hoipin-8, PDB code: 6sc9:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the DAB3/Hoip-Rbr-Hoipin-8


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of DAB3/Hoip-Rbr-Hoipin-8 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2011 b:55.5 occ:1.00 N B:GLY104 3.0 52.2 1.0 N A:TRP798 3.5 50.3 1.0 CA B:ARG103 3.7 48.6 1.0 CD A:LYS829 3.8 63.7 1.0 C B:ARG103 3.8 56.8 1.0 CA B:GLY104 3.9 43.5 1.0 CE A:LYS829 4.0 63.0 1.0 CD2 A:LEU797 4.0 68.0 1.0 CA A:LEU797 4.0 53.7 1.0 CD1 A:TRP798 4.1 53.8 1.0 O A:PHE796 4.1 61.6 1.0 NZ A:LYS829 4.1 61.6 1.0 N B:THR105 4.2 51.2 1.0 CB A:TRP798 4.2 56.7 1.0 C A:LEU797 4.3 67.2 1.0 O A:TRP798 4.4 64.0 1.0 CG B:ARG103 4.4 68.3 1.0 CA A:TRP798 4.4 49.2 1.0 CB B:ARG103 4.4 52.3 1.0 C B:GLY104 4.4 44.8 1.0 O B:SER102 4.5 56.4 1.0 CG A:TRP798 4.6 57.8 1.0 CG A:LYS829 4.7 49.8 1.0 CB A:LEU797 4.8 49.5 1.0 N B:ARG103 4.8 59.8 1.0 C A:TRP798 4.9 55.7 1.0 O B:THR105 4.9 51.0 1.0 O A:HOH2128 4.9 64.3 1.0 C A:PHE796 5.0 65.6 1.0

Chlorine binding site 2 out of 2 in the DAB3/Hoip-Rbr-Hoipin-8


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of DAB3/Hoip-Rbr-Hoipin-8 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl202 b:79.0 occ:1.00 OG1 B:THR28 3.3 83.2 1.0 OH B:TYR32 3.6 65.2 1.0 N B:THR28 3.8 71.0 1.0 CB B:THR28 4.1 75.3 1.0 CE1 B:TYR32 4.2 53.9 1.0 CA B:PHE27 4.4 59.7 1.0 CB B:PHE27 4.4 67.0 1.0 CZ B:TYR32 4.4 63.3 1.0 CA B:THR28 4.6 66.4 1.0 C B:PHE27 4.6 60.5 1.0

Y.-C.I.Tsai, D.House, K.Rittinger. DAB3/Hoip-Rbr Apo Structure Cell Chem Biol 2019.
ISSN: ESSN 2451-9456