|
Chlorine in PDB 6spt: High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal ActivityProtein crystallography data
The structure of High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity, PDB code: 6spt
was solved by
V.Napolitano,
M.Dawidowski,
V.C.Kalel,
R.Fino,
L.Emmanouilidis,
D.Lenhart,
M.Ostertag,
M.Kaiser,
M.Kolonko,
W.Schilebs,
P.Maser,
I.Tetko,
K.Hadian,
O.Plettenburg,
R.Erdmann,
M.Sattler,
G.M.Popowicz,
G.Dubin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity
(pdb code 6spt). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity, PDB code: 6spt: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 6sptGo back to Chlorine Binding Sites List in 6spt
Chlorine binding site 1 out
of 4 in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 6sptGo back to Chlorine Binding Sites List in 6spt
Chlorine binding site 2 out
of 4 in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 6sptGo back to Chlorine Binding Sites List in 6spt
Chlorine binding site 3 out
of 4 in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 6sptGo back to Chlorine Binding Sites List in 6spt
Chlorine binding site 4 out
of 4 in the High Resolution Crystal Structure of N-Terminal Domain of PEX14 From Trypanosoma Brucei in Complex with the Fist Compound with Sub- Micromolar Trypanocidal Activity
Mono view Stereo pair view
Reference:
M.Dawidowski,
V.C.Kalel,
V.Napolitano,
R.Fino,
K.Schorpp,
L.Emmanouilidis,
D.Lenhart,
M.Ostertag,
M.Kaiser,
M.Kolonko,
B.Tippler,
W.Schliebs,
G.Dubin,
P.Maser,
I.Tetko,
K.Hadian,
O.Plettenburg,
R.Erdmann,
M.Sattler,
G.M.Popowicz.
Structure-Activity Relationship in Pyrazolo[4,3-C]Pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction (Ppi) with Trypanocidal Activity. J.Med.Chem. 2019.
Page generated: Sat Dec 12 13:40:49 2020
ISSN: ISSN 0022-2623 PubMed: 31860309 DOI: 10.1021/ACS.JMEDCHEM.9B01876 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |