Chlorine in PDB 6t2x: 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A.

All present enzymatic activity of 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A.:
2.7.7.48; 3.4.22.66; 3.6.1.15;

The structure of 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A., PDB code: 6t2x was solved by J.Guo, J.B.Cooper, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.70 / 1.54
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	62.890, 89.360, 61.440, 90.00, 96.73, 90.00
R / Rfree (%)	13.7 / 19.8

The binding sites of Chlorine atom in the 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A. (pdb code 6t2x). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A., PDB code: 6t2x:

Chlorine binding site 1 out of 1 in the 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 3C-Like Protease From Southampton Virus Complexed with FMOPL000004A. within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:31.3 occ:0.90 CL10 B:JFJ201 0.0 31.3 0.9 C08 B:JFJ201 1.7 29.6 1.0 C07 B:JFJ201 2.7 29.8 1.0 C09 B:JFJ201 2.7 31.8 1.0 NH2 B:ARG100 3.7 26.5 1.0 CZ B:ARG100 3.8 19.1 1.0 NH1 B:ARG100 3.9 18.8 1.0 C06 B:JFJ201 4.0 32.6 1.0 C04 B:JFJ201 4.0 30.6 1.0 C05 B:JFJ201 4.5 32.0 1.0 NE B:ARG100 4.6 25.9 1.0

J.Guo, A.Douangamath, W.Song, A.R.Coker, A.W.E.Chan, S.P.Wood, J.B.Cooper, E.Resnick, N.London, F.V.Delft. In Crystallo-Screening For Discovery of Human Norovirus 3C-Like Protease Inhibitors. J Struct Biol X V. 4 00031 2020.
ISSN: ESSN 2590-1524
PubMed: 32743543
DOI: 10.1016/J.YJSBX.2020.100031