Chlorine in PDB 6t50: Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark

The structure of Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark, PDB code: 6t50 was solved by R.M.J.M.De Vries, F.A.Meijer, L.Brunsveld, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	93.81 / 1.87
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	108.325, 108.325, 108.509, 90.00, 90.00, 120.00
R / Rfree (%)	18.6 / 21

The binding sites of Chlorine atom in the Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark (pdb code 6t50). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark, PDB code: 6t50:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:44.4 occ:1.00 CL1 A:MJE602 0.0 44.4 1.0 C16 A:MJE602 1.7 48.4 1.0 C15 A:MJE602 2.7 41.2 1.0 C17 A:MJE602 2.7 46.6 1.0 C14 A:MJE602 3.0 45.8 1.0 N2 A:MJE602 3.3 45.9 1.0 N1 A:MJE602 3.4 47.0 1.0 C A:LEU324 3.5 41.4 1.0 CB A:LEU324 3.6 35.7 1.0 N A:THR325 3.6 40.6 0.1 N A:THR325 3.6 39.6 0.9 O A:LEU324 3.7 41.7 1.0 O3 A:MJE602 3.7 43.0 1.0 OG1 A:THR325 3.8 39.6 0.9 CE A:MET358 3.8 52.0 1.0 CA A:THR325 3.8 41.1 0.9 CA A:THR325 3.9 42.3 0.1 CG1 A:ILE328 3.9 39.4 1.0 C20 A:MJE602 4.0 54.8 1.0 C18 A:MJE602 4.0 40.9 1.0 CA A:LEU324 4.1 35.9 1.0 CG2 A:THR325 4.2 43.1 0.1 C4 A:MJE602 4.2 41.1 1.0 CD1 A:LEU483 4.3 40.1 1.0 C6 A:MJE602 4.4 43.3 1.0 C19 A:MJE602 4.5 43.8 1.0 CB A:THR325 4.6 43.7 0.9 CB A:THR325 4.6 43.2 0.1 CB A:ILE328 4.7 40.5 1.0 O A:ALA321 4.7 37.2 1.0 C5 A:MJE602 4.8 44.2 1.0 CG A:LEU324 4.8 39.6 1.0 CD1 A:ILE328 4.9 42.8 1.0 C8 A:MJE602 5.0 37.9 1.0

Chlorine binding site 2 out of 2 in the Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Ror(Gamma)T Ligand Binding Domain in Complex with 25- Hydroxycholesterol and Allosteric Ligand Glenmark within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:53.6 occ:1.00 CL2 A:MJE602 0.0 53.6 1.0 C20 A:MJE602 1.7 54.8 1.0 C19 A:MJE602 2.7 43.8 1.0 C15 A:MJE602 2.7 41.2 1.0 OE1 A:GLN484 3.0 69.5 0.4 C14 A:MJE602 3.0 45.8 1.0 O3 A:MJE602 3.3 43.0 1.0 CD A:GLN484 3.4 64.9 0.4 CD1 A:LEU505 3.5 93.4 1.0 CG A:GLN484 3.8 59.9 0.6 N2 A:MJE602 3.9 45.9 1.0 C18 A:MJE602 4.0 40.9 1.0 C16 A:MJE602 4.0 48.4 1.0 NE2 A:GLN484 4.0 60.5 0.4 CG A:GLN484 4.1 60.4 0.4 CB A:LEU483 4.2 39.3 1.0 C A:LEU483 4.3 49.4 1.0 N1 A:MJE602 4.3 47.0 1.0 O A:LEU483 4.3 48.6 1.0 N A:GLN484 4.4 48.8 1.0 CA A:GLN484 4.4 50.3 0.6 CA A:GLN484 4.4 51.4 0.4 O A:LEU505 4.4 0.6 1.0 C17 A:MJE602 4.5 46.6 1.0 CB A:GLN487 4.6 51.5 1.0 CE2 A:PHE506 4.6 73.9 1.0 CZ A:PHE506 4.6 95.6 1.0 CG A:LEU505 4.7 86.6 1.0 CB A:GLN484 4.8 57.2 0.6 C4 A:MJE602 4.8 41.1 1.0 CB A:GLN484 4.9 56.7 0.4 CG A:GLN487 4.9 60.7 1.0 CA A:LEU483 4.9 43.5 1.0 CD2 A:LEU505 4.9 80.4 1.0 CD A:GLN484 4.9 61.4 0.6 NE2 A:GLN484 4.9 61.3 0.6

R.M.J.M.De Vries, F.A.Meijer, R.G.Doveston, L.Brunsveld. Ror(Gamma)T Ligand Binding Domain in Complex with 25-Hydroxycholesterol and Allosteric Ligand Glenmark To Be Published.