|
Chlorine in PDB 6t5j: Structure of NUDT15 in Complex with Inhibitor TH1760Enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH1760
All present enzymatic activity of Structure of NUDT15 in Complex with Inhibitor TH1760:
3.6.1.9; Protein crystallography data
The structure of Structure of NUDT15 in Complex with Inhibitor TH1760, PDB code: 6t5j
was solved by
M.Carter,
D.Rehling,
M.Desroses,
S.M.Zhang,
A.Hagenkort,
N.C.K.Valerie,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6t5j:
The structure of Structure of NUDT15 in Complex with Inhibitor TH1760 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of NUDT15 in Complex with Inhibitor TH1760
(pdb code 6t5j). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of NUDT15 in Complex with Inhibitor TH1760, PDB code: 6t5j: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6t5jGo back to Chlorine Binding Sites List in 6t5j
Chlorine binding site 1 out
of 2 in the Structure of NUDT15 in Complex with Inhibitor TH1760
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6t5jGo back to Chlorine Binding Sites List in 6t5j
Chlorine binding site 2 out
of 2 in the Structure of NUDT15 in Complex with Inhibitor TH1760
Mono view Stereo pair view
Reference:
S.M.Zhang,
M.Desroses,
A.Hagenkort,
N.C.K.Valerie,
D.Rehling,
M.Carter,
O.Wallner,
T.Koolmeister,
A.Throup,
A.S.Jemth,
I.Almlof,
O.Loseva,
T.Lundback,
H.Axelsson,
S.Regmi,
A.Sarno,
A.Kramer,
L.Pudelko,
L.Brautigam,
A.Rasti,
M.Gottmann,
E.Wiita,
J.Kutzner,
T.Schaller,
C.Kalderen,
A.Cazares-Korner,
B.D.G.Page,
R.Krimpenfort,
S.Eshtad,
M.Altun,
S.G.Rudd,
S.Knapp,
M.Scobie,
E.J.Homan,
U.W.Berglund,
P.Stenmark,
T.Helleday.
Development of A Chemical Probe Against NUDT15. Nat.Chem.Biol. V. 16 1120 2020.
Page generated: Sat Dec 12 13:43:02 2020
ISSN: ESSN 1552-4469 PubMed: 32690945 DOI: 10.1038/S41589-020-0592-Z |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |