Chlorine in PDB 6td4: IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure

The structure of IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure, PDB code: 6td4 was solved by J.A.Tucker, M.P.Martin, L.Z.Wang, C.Jennings, R.Heath, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.28 / 1.71
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	66.874, 67.457, 69.884, 90.00, 90.00, 90.00
R / Rfree (%)	21.7 / 24.5

The binding sites of Chlorine atom in the IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure (pdb code 6td4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure, PDB code: 6td4:

Chlorine binding site 1 out of 1 in the IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of IRF4 Dna-Binding Domain Surface Entropy Mutant Apo Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:89.3 occ:1.00 NH2 A:ARG51 3.3 72.4 1.0 NH1 A:ARG51 3.3 52.9 1.0 CZ A:ARG51 3.7 59.6 1.0 O A:HOH396 4.3 53.0 1.0 OH A:TYR122 4.6 43.8 1.0 NE A:ARG51 4.9 45.1 1.0 O A:HOH427 4.9 51.3 1.0

N.J.Tatum, R.Scott, G.M.Doody, I.Hickson, C.Jennings, M.P.Martin, R.M.Tooze, J.A.Tucker, A.Wittner, L.Z.Wang, E.K.Wright, S.R.Wedge, M.E.M.Noble. Cancer-Associated Mutations in the IRF4 Dna-Binding Domain Confer No Disadvantage in Dna-Binding Affinity and May Increase Transcriptional Activity To Be Published.