|
Chlorine in PDB 6ten: Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).Enzymatic activity of Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).
All present enzymatic activity of Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).:
2.1.1.43; Protein crystallography data
The structure of Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11)., PDB code: 6ten
was solved by
C.Scheufler,
F.Stauffer,
C.Be,
H.Moebitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ten:
The structure of Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11). also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).
(pdb code 6ten). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11)., PDB code: 6ten: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6tenGo back to Chlorine Binding Sites List in 6ten
Chlorine binding site 1 out
of 2 in the Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6tenGo back to Chlorine Binding Sites List in 6ten
Chlorine binding site 2 out
of 2 in the Crystal Structure of DOT1L in Complex with An Inhibitor (Compound 11).
Mono view Stereo pair view
Reference:
F.Stauffer,
A.Weiss,
C.Scheufler,
H.Mobitz,
C.Ragot,
K.S.Beyer,
K.Calkins,
D.Guthy,
M.Kiffe,
B.Van Eerdenbrugh,
R.Tiedt,
C.Gaul.
New Potent DOT1L Inhibitors Forin Vivoevaluation in Mouse. Acs Med.Chem.Lett. V. 10 1655 2019.
Page generated: Sat Dec 12 13:44:01 2020
ISSN: ISSN 1948-5875 PubMed: 31857842 DOI: 10.1021/ACSMEDCHEMLETT.9B00452 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |