Chlorine in PDB 6tun: Helicase Domain Complex

All present enzymatic activity of Helicase Domain Complex:
3.6.4.12;

The structure of Helicase Domain Complex, PDB code: 6tun was solved by F.Sauer, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.71 / 2.07
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	74.940, 78.350, 92.330, 90.00, 90.00, 90.00
R / Rfree (%)	19.2 / 22.7

The binding sites of Chlorine atom in the Helicase Domain Complex (pdb code 6tun). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Helicase Domain Complex, PDB code: 6tun:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Helicase Domain Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Helicase Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:58.3 occ:1.00 O A:HOH652 2.7 64.2 1.0 NE A:ARG373 3.2 39.8 0.6 NH1 A:ARG373 3.5 40.9 0.6 NE A:ARG373 3.7 38.4 0.4 CB A:LYS370 3.7 38.7 1.0 CZ A:ARG373 3.8 40.4 0.6 CA A:LYS370 3.9 33.4 1.0 N A:LYS370 4.0 34.5 1.0 CG A:ARG369 4.1 42.8 1.0 NH2 A:ARG373 4.1 36.5 0.4 CD A:ARG369 4.1 44.4 1.0 O A:HOH647 4.1 50.5 1.0 CG A:LYS370 4.2 41.1 1.0 CD A:ARG373 4.3 36.9 0.6 CZ A:ARG373 4.3 39.5 0.4 CB A:ARG369 4.4 41.1 1.0 NE A:ARG369 4.5 41.9 1.0 C A:ARG369 4.5 35.0 1.0 CD A:ARG373 4.6 37.8 0.4 CZ A:ARG369 4.9 47.8 1.0 CE A:LYS370 4.9 52.0 1.0 NH1 A:ARG369 4.9 52.3 1.0

Chlorine binding site 2 out of 2 in the Helicase Domain Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Helicase Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:55.2 occ:1.00 NE B:ARG373 3.3 37.5 0.5 NH2 B:ARG373 3.5 40.5 0.5 NH1 B:ARG373 3.8 40.3 0.5 CB B:LYS370 3.8 46.0 1.0 CZ B:ARG373 3.8 43.8 0.5 O B:HOH654 3.9 51.0 1.0 CA B:LYS370 4.0 41.2 1.0 N B:LYS370 4.0 41.1 1.0 CD B:ARG369 4.2 45.4 1.0 CG B:ARG369 4.2 44.8 1.0 CD B:ARG373 4.4 38.0 0.5 CD B:ARG373 4.4 37.8 0.5 CB B:ARG369 4.4 43.0 1.0 CG B:LYS370 4.5 48.3 1.0 NE B:ARG369 4.6 44.1 1.0 C B:ARG369 4.7 40.8 1.0 CE B:LYS370 4.7 60.6 1.0 CZ B:ARG373 4.9 40.5 0.5

S.Peissert, F.Sauer, D.B.Grabarczyk, C.Braun, G.Sander, A.Poterszman, J.M.Egly, J.Kuper, C.Kisker. In Tfiih the Arch Domain of Xpd Is Mechanistically Essential For Transcription and Dna Repair. Nat Commun V. 11 1667 2020.
ISSN: ESSN 2041-1723
PubMed: 32245994
DOI: 10.1038/S41467-020-15241-9