Chlorine in PDB 6ud7: Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam

The structure of Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam, PDB code: 6ud7 was solved by D.E.Bussiere, W.Shu, L.Xie, M.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	69.10 / 2.30
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	81.032, 93.778, 264.639, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 24.8

The binding sites of Chlorine atom in the Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam (pdb code 6ud7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam, PDB code: 6ud7:

Chlorine binding site 1 out of 1 in the Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Full-Length Human DCAF15-DDB1(Deltabpb)-DDA1- RBM39 in Complex with Indisulam within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:54.8 occ:1.00 CL A:EF6702 0.0 54.8 1.0 C3 A:EF6702 1.7 54.4 1.0 C2 A:EF6702 2.8 51.6 1.0 C4 A:EF6702 2.8 55.0 1.0 C5 A:EF6702 3.4 52.0 1.0 CG2 A:THR230 3.6 50.7 1.0 CG2 A:VAL556 3.9 48.9 1.0 N1 A:EF6702 4.0 54.5 1.0 C1 A:EF6702 4.0 52.1 1.0 CB A:ARG552 4.2 40.9 1.0 CB A:THR230 4.2 53.4 1.0 O A:ARG552 4.3 50.3 1.0 CG A:ARG552 4.4 45.5 1.0 CA C:MET265 4.4 47.9 1.0 O C:MET265 4.4 50.6 1.0 CA C:GLY268 4.6 49.7 1.0 OG1 A:THR230 4.6 51.6 1.0 CG C:MET265 4.6 52.0 1.0 CD A:ARG552 4.8 52.5 1.0 C6 A:EF6702 4.8 53.0 1.0 CA A:ARG552 4.8 42.7 1.0 CB C:MET265 4.9 49.2 1.0 C A:ARG552 4.9 48.7 1.0 CG1 A:VAL477 4.9 44.3 1.0 C C:MET265 4.9 51.4 1.0 C C:GLY268 5.0 51.6 1.0

D.E.Bussiere, X.Lili, L.Xie, S.Honnappa, W.Shu, A.Burke, C.Be, J.Zhao, A.Godbole, D.King, R.Karki, V.Hornak, F.Xu, J.Cobb, N.Carte, A.O.Frank, A.Frommlet, P.Graff, M.Knapp, A.Fazal, B.Okram, J.Songchun, P.Y.Michellys, R.Beckwith, H.Voshol, C.Wiesmann, J.Solomon, J.Paulk. The Structural Basis of Indisulam-Mediated Recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 Ligase Complex To Be Published.