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Atomistry » Chlorine » PDB 6udt-6uqu » 6udx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6udt-6uqu » 6udx » |
Chlorine in PDB 6udx: X-Ray Co-Crystal Structure of Compound 7 with Mcl-1Protein crystallography data
The structure of X-Ray Co-Crystal Structure of Compound 7 with Mcl-1, PDB code: 6udx
was solved by
X.Huang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the X-Ray Co-Crystal Structure of Compound 7 with Mcl-1
(pdb code 6udx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the X-Ray Co-Crystal Structure of Compound 7 with Mcl-1, PDB code: 6udx: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 6udxGo back to Chlorine Binding Sites List in 6udx
Chlorine binding site 1 out
of 2 in the X-Ray Co-Crystal Structure of Compound 7 with Mcl-1
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 6udxGo back to Chlorine Binding Sites List in 6udx
Chlorine binding site 2 out
of 2 in the X-Ray Co-Crystal Structure of Compound 7 with Mcl-1
Mono view Stereo pair view
Reference:
G.Rescourio,
A.Z.Gonzalez,
S.Jabri,
B.Belmontes,
G.Moody,
D.Whittington,
X.Huang,
S.Caenepeel,
M.Cardozo,
A.C.Cheng,
D.Chow,
H.Dou,
A.Jones,
R.C.Kelly,
Y.Li,
M.Lizarzaburu,
M.C.Lo,
R.Mallari,
C.Meleza,
Y.Rew,
S.Simonovich,
D.Sun,
S.Turcotte,
X.Yan,
S.G.Wong,
E.Yanez,
M.Zancanella,
J.Houze,
J.C.Medina,
P.E.Hughes,
S.P.Brown.
Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring An Alpha-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. J.Med.Chem. V. 62 10258 2019.
Page generated: Mon Jul 29 15:53:04 2024
ISSN: ISSN 0022-2623 PubMed: 31736296 DOI: 10.1021/ACS.JMEDCHEM.9B01310 |
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